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A Novel Effect of Acyclovir on Hair Growth in BALB/c Mice: A Promising Future for Finding a New Topical Drug for the Treatment of Hirsutism

research
A Novel Effect of Acyclovir on Hair Growth in BALB/c Mice: A Promising Future for Finding a New Topical Drug for the Treatment of Hirsutism

1 citations , April 2020 in “Clinical, Cosmetic and Investigational Dermatology”

Acyclovir cream may slow down hair growth, suggesting it could be a new treatment for excessive hairiness.

research RNase L represses hair follicle regeneration through altered innate immune signaling

November 2025

RNase L hinders hair follicle regeneration by altering immune signals.

research Bilateral non-specific orbital inflammation (orbital "pseudotumour"), posterior scleritis, and anterior uveitis associated with hypothyroidism in a child

15 citations , August 2002 in “British Journal of Ophthalmology”

Intralesional cidofovir might be a viable alternative treatment for certain conditions.

research Finasteride Induces Epigenetic Alteration of TMPRss2 Gene Expression: A Potential role in Severe Acute Respiratory Syndrome-Corona Virus-2 Inhibition

May 2023

Finasteride may help reduce COVID-19 infection by altering a key gene.

research Demodex folliculitis

36 citations , March 2004 in “AIDS”

Demodex folliculitis can occur in HIV patients on HAART, and treatment may involve topical creams or medication changes.

research Both Retinoic Acid Receptors α (RARα) and γ (RARγ) Are Able to Initiate Mouse Upper-Lip Skin Glandular Metaplasia

10 citations , August 1998 in “Journal of Investigative Dermatology”

research Oral retinoids-present status

108 citations , November 1980 in “British Journal of Dermatology”

Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.

research Chemotherapy of psoriasis and other skin disorders with oral retinoids

31 citations , January 1981 in “Pharmacology & Therapeutics”

Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.

research ACE2 and TMPRSS2 Potential Involvement in Genetic Susceptibility to SARS-COV-2 in Cancer Patients

38 citations , January 2020 in “Cell Transplantation”

Targeting ACE2 and TMPRSS2 may help prevent or treat COVID-19 in cancer patients.

research A review on computer‐aided chemogenomics and drug repositioning for rationalCOVID‐19 drug discovery

48 citations , August 2022 in “Chemical Biology & Drug Design”

Computer-aided methods can speed up COVID-19 drug discovery and help find new uses for existing drugs.

research Syphilis and Beyond: A Comprehensive Analysis of Associated Infections and Comorbidities in a Five-Year Retrospective Study in the United Arab Emirates (2018-2022)

April 2024 in “International Journal of Sexually Transmitted Diseases”

Syphilis cases and re-infections increased, highlighting the need for ongoing prevention and treatment.

research Dormant tumor cells in ret transgenic mouse melanoma model and their interaction with memory T cells

January 2012 in “heiDOK (Heidelberg University)”

Dormant melanoma cells in mice interact minimally with memory T cells due to a suppressive tumor environment.

research Long-Term Survival of Type XVII Collagen Revertant Cells in an Animal Model of Revertant Cell Therapy

27 citations , July 2013 in “Journal of Investigative Dermatology”

Revertant cell therapy shows promise for treating type XVII collagen deficiency, but better cell selection methods are needed.

research Genetic defects of brain immunity in childhood herpes simplex encephalitis

23 citations , November 2024 in “Nature”

research Effects of testosterone replacement therapy on sexual interest, function, and behavior in HIV+ men

10 citations , January 1997 in “The journal of sex research/The Journal of sex research”

Testosterone replacement therapy significantly improved sexual interest and function in HIV+ men.

research Studying SARS-CoV-2 infectivity and therapeutic responses with complex organoids

36 citations , August 2021 in “Nature Cell Biology”

Organoids can help study COVID-19 and develop treatments, but face challenges like instability and limited renewal.

research Particle-based transcutaneous administration of HIV-1 p24 protein to human skin explants and targeting of epidermal antigen presenting cells

30 citations , January 2014 in “Journal of Controlled Release”

This method is effective for needle-free HIV-1 vaccination by activating immune responses in the skin.

research Antiviral effects of human placenta hydrolysate (Laennec®) against SARS-CoV-2 in vitro and in the ferret model

13 citations , October 2021 in “The Journal of Microbiology”

Human placenta hydrolysate may help treat COVID-19 by reducing virus replication and boosting immune response.

research Nail, hair and skin hyperpigmentation associated with indinavir therapy

15 citations , July 2004 in “AIDS”

Indinavir therapy can cause reversible skin, hair, and nail darkening.

research Dystrophic-Anagen Effluvium Occurring During Pegylated Interferon-α-2a/Ribavirin Therapy

2 citations , March 2015 in “Hepatitis Monthly”

A woman's hair loss during Hepatitis C treatment with PEG-INF-a-2a and Ribavirin was reversible after stopping the medication.

research High dose interferon treatment in chronic hepatitis C.

36 citations , January 1993 in “Gut”

High-dose interferon is effective for chronic hepatitis C but often causes flu-like symptoms.

research HIV/AIDS and Dermatological Findings at A Glance: What Has Changedin the ART Era

April 2026 in “Current HIV Research”

Skin disorders in HIV patients have shifted, with more sexually transmitted infections and ART-related conditions now common.

research Noncoding dsRNA induces retinoic acid synthesis to stimulate hair follicle regeneration via TLR3

47 citations , June 2019 in “Nature Communications”

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

research 1446 RNase L acts as a regeneration suppressor

April 2023 in “Journal of Investigative Dermatology”

RNase L suppresses regeneration in mammals.

research Pitfalls of PCR-Based Strategy for Genotyping Cre-Loxp Mice

6 citations , March 2007 in “BioTechniques”

PCR genotyping in cre-loxP mice can be inaccurate due to unintended gene deletions in non-target tissues.

research A new mutation Rim3 resembling Re den is mapped close to retinoic acid receptor alpha (Rara) gene on mouse Chromosome 11

76 citations , January 1998 in “Mammalian Genome”

research Monkeypox: A Histopathological and Transmission Electron Microscopy Study

5 citations , July 2023 in “Microorganisms”

The study found specific skin and cell changes in patients with monkeypox, helping diagnose and understand the disease.

research Cutaneous Adverse Events in Patients with Chronic Hepatitis C during Treatment with Directly Acting Antiviral Agents: A cohort study

July 2024 in “The Egyptian Journal of Hospital Medicine”

34% of patients on hepatitis C treatment had reversible skin issues.

research 575 INTASYL self-delivering RNAi: A flexible platform to treat dermatological malignancies

July 2024 in “Journal of Investigative Dermatology”

INTASYL is a promising, adaptable RNAi technology for treating skin cancers.

research Prenatal serological diagnosis of intrauterine cytomegalovirus infection.

39 citations , June 1982 in “The BMJ”

Blood tests confirmed a baby in the womb had a CMV infection.

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