42 citations
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December 2016 in “Cell Death & Differentiation” Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.
40 citations
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November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” S100A3 protein is crucial for hair shaft formation in mice.
39 citations
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March 2008 in “Journal of biological chemistry/The Journal of biological chemistry” GLI2 increases follistatin production in human skin cells.
37 citations
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March 2006 in “Regulatory Peptides” Mice skin has components that could help with hair growth and might be used for diabetes treatment.
34 citations
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May 2012 in “International Journal of Molecular Sciences” Dieckol from Ecklonia cava may help hair growth and could be a potential hair loss treatment.
30 citations
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October 2014 in “PLOS ONE” BAF200 is essential for proper heart and coronary artery formation.
29 citations
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January 2013 in “International Journal of Medical Sciences” Wnt10b helps hair follicle cells mature and produce pigment.
29 citations
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March 2012 in “Stem Cell Research & Therapy” Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.
28 citations
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September 2019 in “International Journal of Nanomedicine” Minoxidil nanoparticles can potentially be a more effective treatment for hair growth than current treatments.
28 citations
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January 2008 in “Journal of medical investigation” Sp6 promotes tooth development by reducing follistatin levels.
27 citations
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August 2018 in “Frontiers in Plant Science” High levels of auxin increase root hair growth by activating RSL2 and producing ROS, while high phosphate levels hinder growth by repressing RSL2.
27 citations
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January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Somatostatin may help protect hair follicles from immune attacks.
26 citations
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December 2011 in “Journal of Investigative Dermatology” New gene identification techniques have improved the understanding and classification of inherited hair disorders.
23 citations
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March 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.
23 citations
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January 2018 in “International Journal of Molecular Medicine” Baicalin helps hair growth by activating specific cell signals and pathways.
20 citations
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October 2018 in “American Journal of Clinical Dermatology” Some drugs can cause skin and hair color changes, often reversible when the drug is stopped.
20 citations
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January 2015 in “Current problems in dermatology” Hair gets thinner, grayer, and changes texture with age due to genetics, environment, and cellular changes, affecting the growth cycle.
19 citations
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January 2015 in “Scientific Reports” GPR39 is linked to certain cells in the sebaceous gland and helps with skin healing.
18 citations
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December 2009 in “Canadian Journal of Animal Science” The BMP2 gene is more active in the early growth phase of Cashmere goat hair and may affect hair regeneration and textile production.
17 citations
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October 2003 in “Brazilian Journal of Medical and Biological Research” The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.
16 citations
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September 2018 in “Scientific reports” Scientists created keratinocyte cell lines from human hair that can differentiate similarly to normal skin cells, offering a new way to study skin biology and diseases.
15 citations
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December 2015 in “PLoS ONE” Fibroblasts can be mistaken for neural cells, so functional validation is needed.
14 citations
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September 2018 in “Biochemical and Biophysical Research Communications” Growing hair cells with dermal cells can potentially treat hair loss.
14 citations
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April 2017 in “Scientific Reports” Using a perfusion system and 3D spheroid culture improves the growth of corneal cell layers for tissue engineering.
14 citations
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October 2000 in “Genomics” Rat dermal papilla cells have unique genes crucial for hair growth.
13 citations
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October 2017 in “Bioscience, Biotechnology, and Biochemistry” Centella asiatica extract may help promote hair growth by blocking a specific cell signaling pathway.
13 citations
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November 2013 in “Journal of Endocrinology/Journal of endocrinology” Vitamin D receptor helps control hair growth genes in skin cells.
11 citations
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October 2020 in “Plant biotechnology journal” Overexpressing SIMK in alfalfa boosts root hair growth, nodule clustering, and shoot biomass.
11 citations
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November 2015 in “Journal of Functional Foods” Hibiscus petals improved blood sugar and stress responses in diabetic rats.
11 citations
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December 2014 in “The American journal of pathology” A gene deletion in mice causes weak protein, immune issues, hair loss, airway problems, and wasting disease.