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      The Pathogenesis of Primary Cicatricial Alopecias

      research The Pathogenesis of Primary Cicatricial Alopecias

      150 citations , October 2010 in “The American Journal of Pathology”
      The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
      K ATP Channels and Cardiovascular Disease

      research K ATP Channels and Cardiovascular Disease

      144 citations , March 2013 in “Circulation Research”
      K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.
      Dermatological Adverse Events with Taxane Chemotherapy

      research Dermatological adverse events with taxane chemotherapy

      141 citations , September 2016 in “European Journal of Dermatology”
      Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.
      TGF-β Family Signaling in Stem Cells

      research TGF-β family signaling in stem cells

      132 citations , August 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects”
      TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.
      Tregs: Where We Are and What Comes Next?

      research Tregs: Where We Are and What Comes Next?

      130 citations , November 2017 in “Frontiers in Immunology”
      The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.
      Stem Cell Heterogeneity and Plasticity in Epithelia

      research Stem Cell Heterogeneity and Plasticity in Epithelia

      129 citations , May 2015 in “Cell Stem Cell”
      Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
      Structural Abnormalities of the Hair Shaft

      research Structural abnormalities of the hair shaft

      126 citations , January 1987 in “Journal of The American Academy of Dermatology”
      The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.
      Alopecia Areata: Pathogenesis And Treatment

      research Alopecia areata: Pathogenesis and treatment

      122 citations , November 1984 in “Journal of the American Academy of Dermatology”
      No single treatment is consistently effective for alopecia areata, and more research is needed.
      Extraskeletal Actions of Vitamin D

      research Extraskeletal actions of vitamin D

      119 citations , July 2016 in “Annals of the New York Academy of Sciences”
      Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.
      Acne: Hormonal Concepts and Therapy

      research Acne: Hormonal concepts and therapy

      118 citations , September 2004 in “Clinics in Dermatology”
      Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.
      Hair Regrowth

      research HAIR REGROWTH

      118 citations , April 1998 in “Dermatologic Clinics”
      Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.
      A Review of Diagnosis and Treatment of Acne in Adult Female Patients

      research A review of diagnosis and treatment of acne in adult female patients

      116 citations , December 2017 in “International Journal of Women's Dermatology”
      Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.
      Smoking and the Skin: Effects and Therapeutic Potential

      research Smoking and the skin

      114 citations , February 2012 in “International Journal of Dermatology”
      Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.
      Drug-Induced Skin, Nail, and Hair Disorders

      research Drug-Induced Skin, Nail and Hair Disorders

      114 citations , January 2007 in “Drug Safety”
      Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.
      Chemotherapy-Induced Alopecia

      research Chemotherapy-induced alopecia

      103 citations , December 2011 in “Journal of the American Academy of Dermatology”
      Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.
      Male Androgenetic Alopecia

      research Male androgenetic alopecia

      100 citations , April 2010 in “Expert Opinion on Pharmacotherapy”
      Hair loss in men treated best with early medication or transplant, new treatments researched.