65 citations
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May 2017 in “Advances in wound care” Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.
63 citations
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September 2009 in “Regenerative Medicine” Scientists found a way to grow human hair cells in a lab that can create new hair when transplanted.
57 citations
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January 2014 in “Cold Spring Harbor Perspectives in Medicine” Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.
57 citations
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February 2013 in “Journal of Dermatological Science” Improving the environment and cell interactions is key for creating human hair in the lab.
55 citations
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April 2017 in “Experimental Dermatology” The document describes a way to isolate and grow human hair follicle cells in 3D to help study hair growth.
54 citations
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June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Disruptions in hair follicle fibroblast dynamics can cause hair growth problems.
50 citations
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March 2017 in “PeerJ” Using finasteride or dutasteride may cause long-lasting erectile dysfunction.
46 citations
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December 2018 in “Genes & Development” Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.
45 citations
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February 2019 in “Journal of Affective Disorders” Melatonin improved mental health and metabolism in women with PCOS.
44 citations
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June 2009 in “Biomaterials” Skin cell clumping for hair growth is improved by a protein called fibronectin, which helps cells stick and move better.
41 citations
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January 2020 in “BioMed Research International” Micrografts improve hair density and thickness without side effects.
41 citations
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September 2010 in “Journal of dermatological science” Bone marrow and umbilical cord stem cells can help grow new hair.
41 citations
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June 2010 in “Journal of Investigative Dermatology” New cells are added to the hair's dermal papilla during the active growth phase.
39 citations
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April 2020 in “IntechOpen eBooks” Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.
38 citations
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January 2006 in “Journal of Cellular Biochemistry” Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.
34 citations
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April 2009 in “Skin Pharmacology and Physiology” Minoxidil affects cell growth in two ways: low doses increase growth, while high doses slow it down and can be toxic.
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December 2000 in “The journal of investigative dermatology/Journal of investigative dermatology” Rat vibrissa follicles are useful for studying hair growth cycles, especially the transition from pro-anagen to anagen.
33 citations
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January 2002 Latanoprost, a glaucoma drug, showed potential for promoting hair growth in bald monkeys, especially at higher doses.
32 citations
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July 2012 in “Stem Cells Translational Medicine” Vitamin D3 can help improve hair growth by enhancing the function of specific skin cells and could be useful in hair regeneration treatments.
32 citations
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February 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Two specific hair keratin genes are active during hair growth and decline as hair transitions to rest.
31 citations
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November 2016 in “Cell Reports” Touch sensitivity in mouse skin decreases during hair growth due to changes in touch receptors.
31 citations
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October 2002 in “Dermatologic Surgery” Minoxidil helps stabilize hair loss, increase density, and reduce shedding after hair transplant surgery.
29 citations
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April 2020 in “Biomolecules” The 3D scaffold helped maintain hair cell traits and could improve hair loss treatments.
29 citations
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April 2019 in “BMJ. British medical journal” Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.
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January 2017 in “Critical Reviews in Therapeutic Drug Carrier Systems” Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.
26 citations
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April 1999 in “Dermatologic Clinics” The long-pulsed alexandrite laser is effective for hair reduction, particularly for light-skinned individuals with dark hair, but caution is needed for darker skin.
25 citations
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April 2012 in “Acta Biomaterialia” Using certain small proteins with a growth factor and specific materials can increase the creation of neurons from stem cells.
25 citations
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August 2010 in “Acta Biomaterialia” Researchers developed a method to grow hair follicle cells for transplantation using a special chip.
24 citations
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January 2021 in “Physiological Research” Testosterone affects brain functions and contributes to sex differences, influencing conditions like autism.
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April 2012 in “Developmental Biology” Dermal papillae cells, important for hair growth, come from multiple cell lines and can be formed by skin cells, regardless of their origin or hair cycle phase. These cells rarely divide, but their ability to shape tissue may contribute to their efficiency in inducing hair growth.