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Two enzyme defects in biotin metabolism cause severe skin, hair, and metabolic issues.

Antiphospholipid syndrome can severely damage adrenal glands, requiring early diagnosis and treatment.

Hepatitis C and alcohol abuse may lead to porphyria cutanea tarda.

Cancer treatments can cause various eye problems, so eye doctors should know how to diagnose and treat these early.

Ruxolitinib helps protect skin stem cells and keeps skin healthy in mice with skin GVHD.

Normal cells outcompete and remove mutant cells in the pancreas with the help of the EphA2 receptor.

Accurate diagnosis of SLE requires extensive testing due to its complex symptoms.

Eculizumab helps reduce blood transfusions and stabilize hemoglobin but increases infection risk and is expensive.

Myoblast transplantation shows promise for treating various muscle and heart conditions.

The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

A 47-year-old man's eyelid swelling didn't improve with basic treatments, so a biopsy was needed.

A woman and her daughter had thallium poisoning from a herbal drink and rodenticide, causing hair loss and other symptoms.

People with Myotonic Dystrophy type 1 are more likely to have certain skin conditions, but not more likely to get skin cancer.

Glucocorticoid treatment improved symptoms in a girl with Satoyoshi disease.

Early diagnosis, decontamination, and supportive care are crucial for managing acute radiation syndrome.

A woman with a skin disorder was found to have hepatitis C, which may be linked, and was safely treated with methotrexate.

Finasteride caused blisters on hands and feet.

A unique gene mutation causes vitamin D-resistant rickets without causing hair loss.

Children with chronic kidney disease often have skin, hair, and nail problems.

Mimosine from lamtoro leaf powder is less harmful to the pancreas than pure mimosine.

Upadacitinib effectively treats pyoderma gangrenosum.

Dialysis patients benefit from water-soluble vitamins but need careful management to avoid risks.

A genetic defect causes males in some Mediterranean populations to be born with ambiguous genitalia and develop male traits at puberty.

All medications can cause skin rashes, often without a clear cause, and better tests are needed to identify these drug-related skin issues.

Sodium valproate caused vomiting in 20% of children under 2 years old, with other side effects like hair loss and loss of appetite also noted.

Proper management and preventative measures can reduce serious adverse events from deoxycholic acid injections for fat reduction.

People with decreased kidney function have higher levels of ethyl glucuronide in their hair.

Trichothiodystrophy involves brittle hair due to low sulfur amino acids, not a transport defect.