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Finasteride, when given in high oral doses to pregnant monkeys, caused genital abnormalities in male fetuses, but not in female fetuses or those exposed to intravenous finasteride.

The Oat mouse model shows mild retinal degeneration, useful for testing treatments.

The GG genotype of the KRT71 gene leads to longer wool in Gansu alpine fine-wool sheep.

HoxC genes are crucial for normal hair and nail development.

CD44 variant changes start alopecia areata, but don't maintain it.

The Hr protein binds to DNA, interacts with p53, and affects cell cycle genes.

A mutation in the KRT74 gene causes woolly hair by affecting hair texture.

A six-year-old boy with excessive hair growth and other symptoms may have a genetic link on chromosome 17q, requiring regular medical follow-ups.

A mutation in the hHb3 gene is linked to the hair disorder monilethrix.

A rare genetic disease causes sparse hair and early blindness due to a gene mutation.

People with X-linked hypohidrotic ectodermal dysplasia have no sweat ducts and less, thinner hair.

PRX102 is essential for rice root hair growth by helping transport substances to the tips.

A variant in the ADAM17 gene causes hair loss by increasing protein degradation through TRIM47.

Three specific mutations in the LIPH gene can cause hair loss by damaging the protein's structure and function.

RU58841, an androgen receptor blocker, significantly increased hair density, thickness, and length in monkeys when applied topically daily for several months.

5α-reductase-2 deficiency causes ambiguous genitalia at birth and affects male sexual development, but individuals often develop male characteristics at puberty.

Sheep breeds show different keratin gene expression in the groin, linked to hair follicle density.

FGF13 gene changes cause excessive hair growth in a rare condition.

Minoxidil treatment improves heart defects in a DiGeorge syndrome model.

Mutations in the FOXN1 gene cause severe immune issues but don't affect hair and nails.

The HtrA1L364P mutation causes brain dysfunction and blood vessel damage.

rRSPO1 protein boosts hair growth by activating a key signaling pathway.

A variant in the KRT31 gene causes a rare hereditary hair disorder called monilethrix.

A 21-year-old male with a rare genetic disorder experienced sudden hair loss and high DHEAS levels, likely due to a condition similar to PCOS, usually seen in women.

Continuous light exposure in rats leads to PCOS-like symptoms and suggests sleep habits might affect the disorder's development.

Boys with less severe EDA mutations in XLHED have milder symptoms and better sweat and hair production.

A protein called GIS3 is important for the growth of root hairs in Arabidopsis by controlling two genes with the help of certain growth signals.

Strontium ranelate helps cartilage growth by blocking a specific cell pathway.

People with rheumatoid arthritis have a higher risk of developing alopecia areata.