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The research cloned keratin 7 genes from humans, mice, and marsupials, found similarities between human and mouse genes, and discovered new areas of K7 expression in mice.

XEDAR triggers a specific signaling pathway in cells.

Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.

A rabbit gene important for hair development was identified and detailed.

Krtap11-1 is important for hair strength and structure.

Inward rectifier potassium channels are important in many body functions and diseases, and could be potential drug targets.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.

NKIRAS2 can suppress certain skin tumors but its effect on cancer varies with context and expression level.

ERULUS controls root hair growth by regulating cell wall composition and pectin activity.

GPRC5D is linked to the formation of hair, nails, and certain tongue areas.

K31 can identify clear secretory cells in human sweat glands.

CLK1 is needed for skin cells to become epidermal cells but not sebocytes.

Mutations in the KRT16 gene can cause skin and nail disorders.

Activating cannabinoid receptor 1 reduces certain keratin levels, potentially aiding psoriasis treatment.

REV7 is crucial for genome stability and cancer treatment, making it a potential target for therapy.

Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.

Igf1r helps regulate hair growth cycles.

Keratin 17 is modified by RSK1 in response to growth and stress, affecting skin growth and stress response.

CXCR2 in skin cells promotes tumor growth.

BRG1 is essential for skin cells to move and heal wounds properly.

Keratin 6A increases skin inflammation, suggesting it could be a target for treating certain skin diseases.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

Brg1 is crucial for hair growth and skin repair by maintaining stem cells and promoting regeneration.

RhoA helps skin stem cells grow, aiding wound healing.

A variant in the KRT31 gene causes a rare hereditary hair disorder called monilethrix.

KRT14 gene variants cause dermatopathia pigmentosa reticularis, affecting nails, teeth, and hair.

Type I keratin genes are closely linked to the rex locus on mouse chromosome 11, affecting hair development.

SK2 channels help control sensory signals in rat muscle spindles and hair follicles.

RPGRIP1L helps skin cells stick together by blocking PKCβII, which can prevent skin blistering like in pemphigus.