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Atypical Hippocampal Glutamate Receptor Coupled to Phospholipase D Controlling Stretch-Sensitivity in Primary Mechanosensory Nerve Endings Is Homomeric Purely Metabotropic GluK2

research The atypical ‘hippocampal’ glutamate receptor coupled to phospholipase D that controls stretch‐sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic GluK2

6 citations , September 2023 in “Experimental physiology”

A special receptor in sensory nerve endings helps control how they respond to stretching.

research JMJD3 and NF-κB-dependent activation of Notch1 gene is required for keratinocyte migration during skin wound healing

54 citations , July 2017 in “Scientific Reports”

JMJD3 and NF-κB activate Notch1, which is essential for skin cell movement and wound healing.

research O04 HPV8 E6 leads to Lrig1+ keratinocyte stem cell expansion

July 2023 in “British journal of dermatology/British journal of dermatology, Supplement”

HPV8 E6 gene causes growth of certain skin stem cells.

research INNOVATIVE APPROACH TO CRC PREVENTION: THE ROLE OF LOW-PENETRATION GENES

January 2024 in “Wiadomości Lekarskie”

Low-penetration genes might help personalize colorectal cancer prevention.

research Detection of lentiviral constructs for release testing of CAR- T cells using digital droplet PCR

1 citations , May 2019 in “Cytotherapy”

The new ddPCR method reliably detects unwanted viruses in CAR-T cell products, ensuring their safety for patients.

research MicroRNA-302 Increases Reprogramming Efficiency via Repression of NR2F2

123 citations , November 2012 in “Stem cells”

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

research Pitfalls of mapping a large Turkish consanguineous family with vertical monilethrix inheritance.

4 citations , January 2009 in “PubMed”

A mutation in the KRT86 gene causes hair fragility in a Turkish family.

research Characterization of New Members of the Human Type II Keratin Gene Family and a General Evaluation of the Keratin Gene Domain on Chromosome 12q13.13

92 citations , February 2005 in “Journal of Investigative Dermatology”

research iRhom2 Mutation Leads to Aberrant Hair Follicle Differentiation in Mice

15 citations , December 2014 in “PLoS ONE”

A mutation in the iRhom2 gene causes hairless mice due to abnormal hair follicle development.

research Genomic Organization and Amplification of the Human Keratin 15 and Keratin 19 Genes

12 citations , January 2000 in “Biochemical and Biophysical Research Communications”

The study mapped keratin 15 and 19 genes, aiding future genetic disorder research.

research A protein kinase target of a PDK1 signalling pathway is involved in root hair growth in Arabidopsis

280 citations , January 2004 in “The EMBO Journal”

AGC2-1 protein is essential for root hair growth in Arabidopsis.

research A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice

9 citations , November 1997 in “British Journal of Dermatology”

research RSPO1, a potent inducer of pancreatic β cell neogenesis

1 citations , May 2025 in “Cell Reports Medicine”

RSPO1 could help create new diabetes treatments by increasing pancreatic β cells.

research Protein kinase C is a key target for attenuation of Leigh syndrome by rapamycin

5 citations , February 2019 in “bioRxiv (Cold Spring Harbor Laboratory)”

Rapamycin may help treat Leigh syndrome by targeting protein kinase C.

research Keratin Gel as Conduit Filler for Peripheral Nerve Regeneration on a Rat Sciatic Nerve Injury Model

January 2010

Keratin gel may help repair damaged nerves.

research An evaluation of the RapidHIT™ ID system for hair roots stained with Diamond™ Nucleic Acid Dye

December 2023 in “Forensic science international. Genetics”

The RapidHIT ID system can effectively get DNA profiles from hair roots with enough cells.

research 085 Post-translational regulation of hair keratins in transfected COS-1 cells

July 1995 in “Journal of Dermatological Science”

research Functional characterization of OR51B5 and OR1G1 in human lung epithelial cells as potential drug targets for non-type 2 lung diseases

4 citations , November 2024 in “Cell Biology and Toxicology”

Blocking certain receptors in the lungs might help treat a specific type of asthma.

research 1372 Modulation of YBX1 phosphorylation determines epidermal stem cell function

April 2023 in “Journal of Investigative Dermatology”

Changing YBX1 protein activity affects skin stem cell function and aging.

research Assembly of Hair Keratins in Transfected Epithelial Cells

5 citations , December 1996 in “Biochemical and Biophysical Research Communications”

Mouse hair keratins mHa1 and mHb4 can't form a strong network on their own in cells.

research The mouse keratin 6 isoforms are differentially expressed in the hair follicle, footpad, tongue and activated epidermis

75 citations , October 1999 in “Differentiation”

Mouse keratin 6 isoforms have different expression patterns in various tissues.

research Distribution of P2X₃‐immunoreactive fibers in hairy and glabrous skin of the rat

41 citations , April 2009 in “Journal of comparative neurology”

P2X₃-IR fibers are widespread in rat skin and likely help detect pain.

research 877 Loss of UBE2N in keratinocytes leads to skin inflammation and immune infiltration through IRAK1/4-mediated processes

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

Removing UBE2N from skin cells causes inflammation and immune response, which can be lessened with specific inhibitors.

research 138: Induction of cellular senescence and hair follicle stem cell dysfunction upon p14ARF and p16Ink4a expression in the skin

July 2014 in “European Journal of Cancer”

p14ARF and p16Ink4a cause hair follicle stem cell aging and dysfunction.

research Correlation analysis of four KRTAP gene polymorphisms and cashmere fiber diameters in two cashmere goat breeds

September 2022 in “Canadian journal of animal science”

Certain gene variations are linked to the thickness of cashmere goat hair.

research Mammalian keratin associated proteins (KRTAPs) subgenomes: disentangling hair diversity and adaptation to terrestrial and aquatic environments

65 citations , September 2014 in “BMC genomics”

Different hair types in mammals are linked to variations in specific protein genes, with changes influenced by their living environments.

research TRPV3 as a Therapeutic Target for Itch

88 citations , April 2012 in “Journal of Investigative Dermatology”

Blocking TRPV3 may help treat itch in dry skin conditions.

DSP c.6310delA p.(Thr2104Glnfs*12) Associates With Arrhythmogenic Cardiomyopathy, Increased Trabeculation, Curly Hair, and Palmoplantar Keratoderma

research DSP c.6310delA p.(Thr2104Glnfs*12) associates with arrhythmogenic cardiomyopathy, increased trabeculation, curly hair, and palmoplantar keratoderma

1 citations , March 2023 in “Frontiers in Cardiovascular Medicine”

A specific gene variant is linked to heart disease, increased heart muscle, curly hair, and thick skin on palms and soles.

research Alopecia in a Novel Mouse Model RCO3 Is Caused by mK6irs1 Deficiency

42 citations , September 2003 in “Journal of Investigative Dermatology”

A missing mK6irs1 gene causes hair loss in mice.

research Sgk3 links growth factor signaling to maintenance of progenitor cells in the hair follicle

53 citations , August 2005 in “The Journal of Cell Biology”

Sgk3 is essential for normal hair follicle growth and maintenance.

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