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The 1298CC genotype in RA patients leads to higher methotrexate toxicity, while the 1298AA genotype results in better treatment response.

Elastic Net DNA methylation clocks are inaccurate for predicting age and health status; a "noise barometer" may better indicate aging and disease.

Changes in KRT17 gene activity linked to wool production in Angora rabbits.

The MTR gene affects wool quality and production in Chinese Merino sheep.

DNA changes in tetraploid wheat improve root growth and nitrogen use.

Methamphetamine affects gene expression in rat whisker follicles, with key genes linked to addiction.

The MDR1 C3435T polymorphism does not significantly affect methotrexate response in rheumatoid arthritis patients.

Fixing DNA errors is crucial to prevent skin cancer.

Hair and nails contain stable RNA, useful for personalized medicine and screening.

SETDB1 is essential for controlling DNA methylation, silencing retrotransposons, and maintaining skin cell health, with its absence leading to skin inflammation and hair loss.

Ribonucleotide excision repair is crucial to prevent skin cancer.

Ribonucleotide excision repair is crucial to prevent skin cancer.

DNA methylation likely doesn't cause different lambskin patterns in Hu sheep.

The environment around the time of conception can change the VTRNA2-1 gene in a way that lasts for years and may affect disease risk.

Methylation of the 5-AR2 gene may cause resistance to Finasteride in BPH patients.

Loss of Dnmt3a and Dnmt3b increases aggressive skin tumors by affecting PPAR-γ.

SET7/9 enzyme affects cell growth and diseases like cancer, diabetes, and obesity.

Proper tissue repair in adult skin requires specific histone hypomethylation.

Certain RNAs may help diagnose alopecia areata by affecting keratin genes.

ceRNA networks offer potential treatments for skin aging and wound healing.

Testosterone treatment may change estrogen receptor methylation in AFAB individuals.

Methionine helps improve hair growth in heat-stressed rabbits.

Double-stranded RNA helps regenerate hair follicles by increasing retinoic acid production and signaling.

TET enzymes are important for skin and hair development by controlling gene activity in specific areas.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

MicroRNAs can reprogram cells into stem cells faster and more efficiently than traditional methods.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

Certain proteins involved in DNA modification may affect the genetic changes in systemic lupus erythematosus and could indicate the disease's activity.

Aging changes skin cells, leading to different DNA methylation and gene activity, affecting cell metabolism and aging signs.

m6A-circHECA may affect cashmere goat hair growth and is possibly controlled by gene promoter methylation.