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research Preclinical Pharmacology, Antitumor Activity, and Development of Pharmacodynamic Markers for the Novel, Potent AKT Inhibitor CCT128930

65 citations , February 2011 in “Molecular cancer therapeutics”

CCT128930 is a promising new drug that effectively targets and inhibits a cancer-related protein, showing potential for cancer treatment.

research A phase I study of MK-5108, an oral aurora A kinase inhibitor, in both monotherapy and in combination with docetaxel in patients with advanced solid tumors.

12 citations , May 2010 in “Journal of Clinical Oncology”

MK-5108 is safe and shows potential against tumors, especially alone.

research 089 Single-cell RNA sequencing defines molecular similarities between patch/plaque-stage mycosis fungoides and atopic dermatitis under dupilumab

July 2024 in “Journal of Investigative Dermatology”

research Tru9I Variant as a Novel Genetic Marker for Vitamin D Deficiency in Alopecia Areata

March 2025 in “Clinical Cosmetic and Investigational Dermatology”

The Tru9I variant in the VDR gene may influence alopecia areata risk and vitamin D levels.

research Hidradenitis suppurativa secondary to treatment with a gamma secretase inhibitor

1 citations , October 2023 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

A man developed skin lesions as a side effect of a gamma secretase inhibitor used for treating a tumor.

Investigation of the Molecular Identity of the Junctional Zone in Human Skin

research 1351 Investigation of the molecular identity of the junctional zone in human

April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

GATA6 is important for maintaining and differentiating cells in a key area of human skin.

research Expanding the Clinical and Mutational Spectrum of Recessive AEBP1-Related Classical-Like Ehlers-Danlos Syndrome

20 citations , February 2019 in “Genes”

The study concludes that mutations in the AEBP1 gene can cause a form of Ehlers-Danlos syndrome and should be considered in diagnosis.

research Hereditary 1,25-dihydroxyvitamin D-resistant rickets with alopecia resulting from a novel missense mutation in the DNA-binding domain of the vitamin D receptor

50 citations , September 2009 in “Molecular Genetics and Metabolism”

A new gene mutation causes vitamin D resistance and rickets, treatable with calcium therapy.

research 231 Novel protocol for the invitro maintenance and expansion of adult epidermal LGR5+ stem cells

December 2019 in “Reproduction Fertility and Development”

A new method helps grow skin stem cells better, which could improve skin grafts for burn victims.

Study of Human Leukocyte Antigen in 13 Cases of Familial Frontal Fibrosing Alopecia: CYP21A2 Gene p.V281L Mutation from Congenital Adrenal Hyperplasia Linked to HLA Class I Haplotype HLA-A*33:01; B*14:02; C*08:02 as a Genetic Marker

research Study of Human Leukocyte Antigen ( HLA ) in 13 cases of familial frontal fibrosing alopecia: CYP 21A2 gene p.V281L mutation from congenital adrenal hyperplasia linked to HLA class I haplotype HLA ‐ A33:01 ; B14:02; C*08:02 as a genetic marker

7 citations , January 2019 in “Australasian Journal of Dermatology”

A genetic marker linked to a type of hair loss was found in most patients studied.

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