research Genetic Fate Mapping Using Site-Specific Recombinases
The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.
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research Unchanged androgen-binding properties of sex hormone-binding globulin in male patients with liver cirrhosis
SHBG binding properties are unchanged in male liver cirrhosis patients.
research Androgen antagonists in androgen target tissues
Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.
research Interventions for morphea
Some treatments like methotrexate with prednisone might help juvenile morphea, but more research is needed to confirm.
research Structural features of the α-type filaments of the inner root sheath cells of the guinea pig hair follicle
α-type filaments in guinea pig hair follicles have unique structural features.
research Dihydrotestosterone-induced hair regrowth inhibition by activating androgen receptor in C57BL6 mice simulates androgenetic alopecia
DHT stops hair regrowth in mice, similar to human hair loss.
research Vesicles: Potential nano carriers for the delivery of skin cosmetics
Vesicular carriers like liposomes may improve cosmetic skin treatment delivery and effectiveness but need more human research.
research Transfollicular enhancement of gel containing cationic niosomes loaded with unsaturated fatty acids in rice (Oryza sativa) bran semi-purified fraction
The gel with special fat-loaded particles from rice bran could be an effective skin treatment for hair loss.
research Role of bulge epidermal stem cells and TSLP signaling in psoriasis
Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.
research Rapid generation of homogenous tumor spheroid microtissues in a scaffold-free platform for high-throughput screening of a novel combination nanomedicine
A new triple drug system using nanoparticles effectively targets breast tumors in 3D models.
research Chapter 17. Selective androgen receptor modulators (SARMs)
Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.
research Vitamin D activates type A natriuretic peptide receptor gene transcription in inner medullary collecting duct cells
Vitamin D boosts a specific gene activity in kidney cells that could improve heart and kidney function.
research The new paradigm for androgenetic alopecia and plant-based folk remedies: 5α-reductase inhibition, reversal of secondary microinflammation and improving insulin resistance
Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.
research Specific inhibition of FGF5-induced cell proliferation by RNA aptamers
RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.
research Induction of Hair Keratins Expression by an Annurca Apple-Based Nutraceutical Formulation in Human Follicular Cells
An apple-based supplement was found to stimulate hair protein production, which may help with hair growth.
research Evidence for multiple, developmentally regulated isoforms of Ptprq on hair cells of the inner ear
Ptprq has multiple forms that change during inner ear development.
research Transfollicular drug delivery: current perspectives
Transfollicular drug delivery is promising but needs more research to improve and understand it better.
research The correlation between alopecia and temperament in rhesus macaques (Macaca mulatta) at four primate facilities
Monkeys with more anxious or inhibited temperaments tend to have less hair loss.
research Treatment of androgen excess in females: Yesterday, today and tomorrow
The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.
research Process Development and Crystallization in Oiling-Out System of a Novel Topical Antiandrogen
In 2017, a new method was created to efficiently produce a topical antiandrogen, a compound used to treat excess sebum and acne, with a high yield and purity.
research Identification of functional circRNAs regulating ovarian follicle development in goats
circCFAP20DC helps goat ovarian cells grow, aiding follicle development.
research Reclassification of Botryococcus braunii chemical races into separate species based on a comparative genomics analysis
Botryococcus braunii's three chemical races should be reclassified as separate species.
research Green formulation of spironolactone loaded chitosan coated nano lipid carrier for treatment of acne vulgaris: a randomized double-blind clinical trial
Chitosan-coated spironolactone nano carriers effectively treat acne without side effects.
research New Insight for Enhanced Topical Targeting of Caffeine for Effective Cellulite Treatment: In Vitro Characterization, Permeation Studies, and Histological Evaluation in Rats
CA-SLN-Ngel significantly reduces cellulite more effectively than regular caffeine gel.
research Differential impact of environmental factors on systemic and localized autoimmunity
Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.
research Hair Follicle Targeting with Nanoparticles
Nanoparticles can be used to deliver drugs to hair follicles, potentially improving treatments for conditions like acne and alopecia, and could also be used for vaccine delivery and gene therapy.
research Development of fluridil, a topical suppressor of the androgen receptor in androgenetic alopecia
Fluridil promotes hair growth safely and effectively for androgenetic alopecia.
research Sustainable applications of phytochemicals and nutritive components derived from selected underutilized seeds: A review [pdf]
Underutilized seeds like jackfruit, Indian almond, and tamarind have valuable nutrients and compounds that can be used sustainably in various industries.
research The use of biodegradable microneedle patches to increase penetration of topical steroid for prurigo nodularis.
Biodegradable microneedle patches help topical steroids work better for prurigo nodularis.
research High-resolution structures of mutants of residues that affect access to the ligand-binding cavity of human lipocalin-type prostaglandin D synthase
Mutations in the enzyme don't significantly change how it binds to its specific substances.