research Tactile sensitivity in the rat: a correlation between receptor structure and function
Rats have different touch receptors in their paws that help with movement and handling objects.
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research Adaptations in the structure and innervation of follicle‐sinus complexes to an aquatic environment as seen in the Florida manatee (Trichechus manatus latirostris)
Manatee whiskers are specially adapted for touch in water.
research Mechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerization
ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.
research Three-dimensional architecture and linearized mapping of vibrissa follicle afferents
Large-scale reconstructions enhance understanding of vibrissal sensory mapping in the brain.
research Follicle architecture and innervation of functionally distinct rat vibrissae
Rat vibrissae structure relates to their sensory function.
research FOXN1: A Master Regulator Gene of Thymic Epithelial Development Program
The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.
research Case 21-2012
The patient was diagnosed with anorexia nervosa and severe malnutrition, requiring urgent refeeding and monitoring.
research The Dynamics of the Skin’s Immune System
The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
research Tactile innervation densities across the whole body
Young adults have about 230,000 tactile nerve fibers, decreasing 5-8% per decade with age.
research Regeneration of skin appendages and nerves: current status and further challenges
Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
research Club-like receptors respond to light touch but not to whisking
Club-like receptors detect light touch but not whisking.
research Np63 Regulates Stem Cell Dynamics in the Mammalian Olfactory Epithelium
p63 is essential for activating and differentiating stem cells in the nose's olfactory tissue.
research BMP-FGF Signaling Axis Mediates Wnt-Induced Epidermal Stratification in Developing Mammalian Skin
Wnt signaling is essential for forming the skin's spinous layer through a BMP-FGF pathway.
research Epidermal Development in Mammals: Key Regulators, Signals from Beneath, and Stem Cells
Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
research Beyond Expectations
Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
research MicroRNA/mRNA regulatory networks in the control of skin development and regeneration
MicroRNAs are crucial for controlling skin development and healing by regulating genes.
research DKK1 Mediated Inhibition of Wnt Signaling in Postnatal Mice Leads to Loss of TEC Progenitors and Thymic Degeneration
Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.
research Involvement of Wnt, Eda and Shh at defined stages of sweat gland development
Wnt, Eda, and Shh pathways are crucial for different stages of sweat gland development in mice.
research Disrupted Ectodermal Organ Morphogenesis in Mice with a Conditional Histone Deacetylase 1, 2 Deletion in the Epidermis
Mice without certain skin proteins had abnormal skin and hair development.
research Oral zinc sulphate causes murine hair hypopigmentation and is a potent inhibitor of eumelanogenesisin vivo
Oral zinc sulphate reduces dark hair color in mice.
research Pan-cancer analysis of microRNA expression profiles highlights microRNAs enriched in normal body cells as effective suppressors of multiple tumor types: A study based on TCGA database
Certain microRNAs found in normal cells can effectively suppress various cancers.
research The overexpression of R-spondin 3 affects hair morphogenesis and hair development along with the formation and maturation of the hair follicle stem cells
Overexpression of R-spondin 3 leads to sparse hair and impaired hair regeneration.
research Transcriptional Control of Epidermal Stem Cells
Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.
research The story of when kidneys fail and the contribution of Air Vice-Marshal Sir Ralph Jackson
Air Vice-Marshal Sir Ralph Jackson significantly advanced dialysis technology in the UK.
research Tackling underrepresentation to aid understanding of Parkinson’s disease: Progress and further opportunities
Addressing underrepresentation in Parkinson's research is crucial for better treatments and understanding.
research Pesquisa e desenvolvimento de produtos cosméticos para o público masculino com óleos essenciais: caracterização da pele, eficácia clínica, perfil de consumo e influência da publicidade
Men's skincare products with essential oils can improve skin health and may increase male interest in cosmetics.
research Concise Review: Tissue-Engineered Skin and Nerve Regeneration in Burn Treatment
New methods for skin and nerve regeneration can improve healing and feeling after burns.
research Modulation of macrophage functions by ECM-inspired wound dressings – a promising therapeutic approach for chronic wounds
ECM-inspired wound dressings can help heal chronic wounds by controlling macrophage activity.
research Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin
Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.
research Drug Repurposing - Hypothesis, Molecular Aspects and Therapeutic Applications
Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.