research Hair transplantation in mice: Challenges and solutions
Researchers successfully transplanted hair follicles in mice, which survived well and helped in wound healing.
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150-180 / 1000+ results research Mechanical stiffness across skin layers in human: a pilot study
The epidermis is the stiffest skin layer.
research Photoepilation: a potential threat to wound healing in a mouse
Photoepilation may disrupt normal wound healing and increase the risk of scars.
research The Role of the Vitamin D Receptor in the Epidermal Stem Cell Response to Wounding
Vitamin D receptor is crucial for skin wound healing.
research Gate keeping the sebaceous gland
The research found that specific stem cells maintain skin gland openings and that disrupting their activity can cause blockages or early cancer signs, indicating a need for targeted treatments.
research Abstract 4385: Live-imaging the interface between homeostasis and cancer initiation
Mutant cells in hair follicles are influenced by their location and interactions with surrounding cells.
research Photo (Chemo) Therapy and Vitiligo
Phototherapy is effective in treating vitiligo.
research Faculty Opinions recommendation of Targeted skin overexpression of the mineralocorticoid receptor in mice causes epidermal atrophy, premature skin barrier formation, eye abnormalities, and alopecia.
Overexpression of a specific receptor in mice skin causes skin thinning, early skin barrier formation, eye issues, and hair loss.
research Clinical Snippets
Glycerol may improve wound healing and prevent keloids, a device can measure itch intensity, male pattern baldness is highly heritable, and fumaric acid esters may work for psoriasis by causing cell death in T cells.
research Anatomy and Function of the Skin
The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.
research What microbes live in the human hair follicle and what is their role?
Different tiny organisms live in human hair follicles and can affect both health and skin conditions, including acne and hair loss.
research Beyond Expectations
Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
research Transgenic mice provide new insights into the role of TGF-alpha during epidermal development and differentiation.
TGF-alpha affects skin thickness, hair growth, and may contribute to psoriasis and papilloma formation.
research Deregulated expression of E2F1 induces hyperplasia and cooperates with ras in skin tumor development
Overexpression of E2F1 can lead to skin tumors and disrupt hair growth.
research Human Peptidylarginine Deiminase Type III: Molecular Cloning and Nucleotide Sequence of the cDNA, Properties of the Recombinant Enzyme, and Immunohistochemical Localization in Human Skin
PAD3 plays a key role in hair and skin protein structure and may be linked to skin diseases.
research Do nanoparticles have a future in dermal drug delivery?
Nanoparticles can improve drug delivery to hair follicles but struggle to penetrate deeper skin layers.
research Learning from nudity: lessons from the nude phenotype
The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.
research The control of hair growth: An overview
Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.
research Topical liposome delivery of molecules to hair follicles in mice
Liposomes can safely and effectively deliver substances to mouse hair follicles, potentially useful for human hair treatments.
research The skinny on slug
Slug is crucial for skin health, hair growth, and healing.
research BLIMP1 Is Required for Postnatal Epidermal Homeostasis but Does Not Define a Sebaceous Gland Progenitor under Steady-State Conditions
BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.
research Dynamic expression of the zinc-finger transcription factor Trps1 during hair follicle morphogenesis and cycling
Trps1 plays a key role in hair follicle development and cycling.
research Expression of the Intermediate Filament Keratin Gene,K15,in the Basal Cell Layers of Epithelia and the Hair Follicle
K15 gene is mainly active in the basal layers of hair follicles and epithelia, aiding early skin cell development.
research Isolation and Molecular Cloning of Epidermal- and Hair Follicle-Specific Peptidylarginine Deiminase (Type III) from Rat
PAD type III enzyme is specific to rat skin and hair follicles.
research Skin aging as a mechanical phenomenon: The main weak links
Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.
research Severe Skin Permeability Barrier Dysfunction in Knockout Mice Deficient in a Fatty Acid ω-Hydroxylase Crucial to Acylceramide Production
Lack of a key enzyme causes severe skin issues and death in mice.
research Acquired perforating dermatosis in renal and diabetic patients
Acquired perforating dermatosis often affects skin in people with kidney issues and diabetes.
research Expression patterns of programmed cell death 4 protein in normal human skin and some representative skin lesions
Increasing PDCD4 protein may help prevent or treat some skin cancers.
research Hair Follicular Expression and Function of Group X Secreted Phospholipase A2 in Mouse Skin
sPLA2-X is crucial for normal hair growth and follicle health.
research Miz1 is required for hair follicle structure and hair morphogenesis
Miz1 is essential for proper hair structure and growth.