December 2025 in “Advanced Healthcare Materials” The Spherical Skin Model improves drug and cosmetic testing by accurately mimicking human skin for efficient compound screening.
351 citations
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February 2010 in “Nature Cell Biology” Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.
340 citations
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September 2014 in “PLOS Genetics” The study found that in Latin America, ancestry varies by location, influences physical traits, and affects how people perceive their own heritage.
330 citations
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December 2009 in “Cell stem cell” SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.
305 citations
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March 2018 in “International journal of molecular sciences” The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.
237 citations
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February 2016 in “Science Translational Medicine” The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.
225 citations
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April 2018 in “Journal of Investigative Dermatology” Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.
202 citations
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August 2017 in “Nature cell biology” Lactate production is important for activating hair growth stem cells.
192 citations
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April 2019 in “ACS nano” A new microneedle patch made from hair proteins helps regrow hair faster and better than current treatments.
190 citations
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October 2002 in “The FASEB journal” Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.
184 citations
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November 2014 in “Developmental Cell” Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.
176 citations
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April 2011 in “Science” Hair stem cell regeneration is controlled by signals that can explain different hair growth patterns and baldness.
175 citations
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December 2014 in “PLoS Biology” Macrophages help activate hair follicle stem cells, affecting hair growth and skin repair.
174 citations
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November 2016 in “Cell stem cell” Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.
166 citations
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August 2010 in “Proceedings of the National Academy of Sciences of the United States of America” Scientists found a new, less invasive way to study body clocks using hair cells, which shows shift workers' body clocks don't match their lifestyles.
150 citations
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June 2014 in “Biomaterials” Peptide hydrogels heal burn wounds faster and better than standard dressings.
149 citations
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June 2002 in “Veterinary record/The veterinary record” Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.
133 citations
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February 2017 in “PLoS Genetics” Genetic factors can help predict male pattern baldness risk.
133 citations
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May 2016 in “Cell Host & Microbe” Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.
132 citations
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January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
123 citations
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November 2012 in “Stem cells” MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.
122 citations
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June 2020 in “Aging” Older age and related diseases increase COVID-19 risk, but anti-aging treatments might help.
114 citations
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March 2018 in “PLOS Medicine” Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.
106 citations
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October 2016 in “Cell Stem Cell” PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.
100 citations
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June 2011 in “Journal of The American Academy of Dermatology” 5% minoxidil foam once daily works as well as 2% minoxidil solution twice daily for female hair growth and is more convenient.
92 citations
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September 2019 in “ACS nano” A wearable device using electric stimulation can significantly improve hair growth.
92 citations
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August 2017 in “Proceedings of the National Academy of Sciences of the United States of America” Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.
82 citations
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September 2018 in “Nature Communications” A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.
78 citations
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August 2012 in “Human molecular genetics online/Human molecular genetics” A new gene, JMJD1C, may affect testosterone levels in men.
77 citations
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July 2020 in “Cell” Muscles and nerves that cause goosebumps also help control hair growth.