143 citations
,
April 2018 in “Electronic physician” More research is needed to confirm safflower's traditional medicinal uses.
12 citations
,
August 2018 in “BMC Biotechnology” A protein found in safflower seeds can stimulate hair growth and speed up wound healing in mice.
7 citations
,
February 2022 in “International Journal of Pharmaceutics” Safflower oil nanoparticles can deliver hFGF10 to hair follicles, reduce inflammation, and potentially speed up hair growth in conditions causing hair loss.
3 citations
,
February 2023 in “ACS omega” Grape seed oil improved hair quality the most, followed by rosehip and safflower seed oils, and reduced damage from shampoo.
October 2025 in “Benha Veterinary Medical Journal” Safflower is the most effective in protecting against liver and kidney damage, followed by silymarin and dandelion.
Safflower extract in nanostructured carriers was more effective than minoxidil for hair growth without irritating skin.
Ozonized sunflower oil effectively heals small animal wounds and promotes hair growth.
37 citations
,
July 2019 in “Pakistan Journal of Biological Sciences” Quinoa and safflower seeds may help fight cancer and protect the liver.
Almond and sunflower seed tofu is high in protein and marketed for diets and vegetarians.
73 citations
,
July 1977 in “Archives of Dermatology” Applying safflower oil to the skin reversed fatty acid deficiency symptoms in 21 days.
39 citations
,
December 2013 in “Phytotherapy Research” Safflower (Carthamus tinctorius) extract helps hair grow and could be used in hair products.
27 citations
,
June 2015 in “Revista Brasileira de Farmacognosia” Safflower has been used in traditional medicine for centuries and shows promise in treating heart, brain, and inflammatory conditions, but more research is needed to ensure its safety.
20 citations
,
September 2015 in “Protein expression and purification” Scientists made safflower seeds produce a human growth factor that could help with hair growth and wound healing.
20 citations
,
May 1985 in “British journal of nutrition” Dietary essential fatty acids improved skin and hair conditions and partially corrected fat composition in diabetic mice.
14 citations
,
July 1977 in “PubMed” Applying linoleic acid to the skin fixed essential fatty acid deficiency symptoms.
14 citations
,
July 1977 in “Archives of Dermatology” Applying linoleic acid to the skin can reverse essential fatty acid deficiency symptoms.
1 citations
,
December 2014 in “International Journal of Pharmacy and Pharmaceutical Sciences” Safflower flower extract in tiny fat-based particles can help hair grow.
The transgenic safflower oil with oleosin-rhFGF9 improved hair growth and wound healing in mice.
January 2013 in “วารสารเภสัชศาสตร์อีสาน (Isan Journal of Pharmaceutical Sciences, IJPS)” Safflower extract increases melanin production in certain skin cells without harming them.
June 2024 in “International Journal of Cosmetic Science” Plant oils like coconut, camellia, and safflower can penetrate hair, making it stronger and softer.
January 2020 in “Der Pharmacia Lettre” Nanoparticle-based herbal remedies could be promising for treating hair loss with fewer side effects and lower cost, but more research is needed.
August 2019 in “Key engineering materials” A microemulsion with Carthamus tinctorius extract effectively inhibits 5α-reductase and improves skin and hair follicle delivery.
January 2013 in “วารสารเภสัชศาสตร์อีสาน (Isan Journal of Pharmaceutical Sciences, IJPS)” Carthamus tinctorius floret extract is a safe hair growth promoter with good skin absorption.
13 citations
,
April 2017 in “Journal of Alternative and Complementary Medicine” Traditional and complementary medicine may help with skin conditions, but more high-quality research is needed.
11 citations
,
January 2006 in “International Journal of Cosmetic Science” Some oils can penetrate hair and reduce the stickiness between fibers, but mineral oil cannot.
1 citations
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December 2021 in “Pakistan biomedical journal” Eating certain seeds may help reduce symptoms of Polycystic Ovary Syndrome.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The herbal hair serum, especially formulation H3, effectively improves hair nourishment, smoothness, and health.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The herbal hair serum, especially formulation H3, effectively improves hair nourishment, smoothness, and health.
January 2026 in “Open Veterinary Journal” PUFA-rich oil improves pet hair quality but may raise triglyceride levels.
August 2025 in “Deleted Journal” Arwa oil promotes healthy hair growth and has antimicrobial benefits.