research Toxicity of Acanthospermum hispidum to mice
Acanthospermum hispidum is toxic to mice, causing death and damage to internal organs.
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810-840 / 1000+ resultsresearch Les cançons de l'escarni
Agaricus bisporus β-Glucan particles could effectively treat cervical cancer and offer antimicrobial and antioxidant benefits.
research Allergies and hair dyes
research ANTINOCICEPTIVE ACTIVITY OF ADIANTUM CAPILLUS IN EXPERIMENTAL ANIMALS
Adiantum capillus extract reduces pain and swelling in animals.
research Pink scaling papules and plaques on the palms, soles, chest, abdomen, and extremities
The woman likely has secondary syphilis, treatable with penicillin.
research A Thallium-Based Screening Procedure to Identify Molecules That Modulate the Activity of Ca2+-Activated Monovalent Cation-Selective Channels
The conclusion is that a new test was created to find substances that affect specific ion channels, and it works well for drug discovery.
research Turmeric Essential Oil Constituents as Potential Drug Candidates: A Comprehensive Overview of Their Individual Bioactivities
Turmeric essential oil compounds have potential as safe, effective drugs.
research Computational metal-flavonoids complexes presentation of greenly synthesized silver nanoparticles combined flavonoids from Lens culinaris L. as anticancer agents using BcL-2 and IspC proteins
The study investigated the use of Lens culinaris L. total extract (LCTE) for synthesizing silver nanoparticles (LC-AgNPs) and evaluated their anticancer and antimicrobial properties. The LC-AgNPs, characterized as spherical with an average size of 19.22 nm, demonstrated potent cytotoxic activity against MCF-7, HCT-116, and HepG2 cancer cell lines, with IC50 values of 0.37, 0.35, and 0.1 µg/mL, respectively. They induced apoptosis and affected cell cycle phases differently across the cell lines. Additionally, LC-AgNPs showed strong antimicrobial activity against Klebsiella pneumoniae and Acinetobacter baumannii. Molecular docking identified Kaempferol-3-O-robinoside-7-O-rhamnoside and Quercetin-3-D-xyloside as key constituents inhibiting Bcl-2 and IspC cancer targets when combined with the nanoparticles.
research 5α‐Reductase Inhibitors
5-Alpha reductase inhibitors help treat enlarged prostate but may cause sexual side effects.
research We-P13:320 The clinical significance of serum 7-ketocholesterol levels in patients with metabolic syndrome or acute myocardial infarction
research Preclinical Development and Phase I Study of ZSYY001 , a Polymeric Micellar Paclitaxel for Advanced Solid Tumor
ZSYY001 is safe, well-tolerated, and shows promise for treating advanced solid tumors.
research Nurses' Drug Alert
Some drugs can cause serious side effects, like hypoglycemia from mix-ups, skin reactions, or depression, and while penicillamine may help rheumatoid arthritis more than auranofin, it has more severe side effects.
research A Filipino with Systemic Lupus Erythematosus-Scleroderma Overlap Syndrome
Recognizing and treating overlap syndrome in connective tissue diseases is crucial.
research Nonsteroidal tissue selective androgen receptor modulators: a promising class of clinical candidates
Selective androgen receptor modulators (SARMs) are a promising type of drug for various health conditions due to their targeted actions.
research Chloroquine and cinchonine affect rat vascular smooth muscle tonus through calcium channels – in silico and in vitro approaches
Chloroquine and cinchonine relax rat blood vessels by affecting calcium channels, with chloroquine needing caution in heart patients.
research NEW FORMULATIONS: Sodium cromoglycate
Lifestyle changes are more effective than medication for reducing type 2 diabetes risk.
research Multiple minute digitate hyperkeratosis
The document concludes that fexofenadine reduces inflammation in chronic hives, cholestyramine helps half of pregnant women with itchy rashes, and relaxing incisions are a good alternative in facial surgery for the elderly.
research Skin and metabolic syndrome: A review of the possible associations
Certain medications can impact metabolic syndrome, with some improving conditions like high blood sugar and others having no effect.
research Design and synthesis of novel androgen receptor antagonists with sterically bulky icosahedral carboranes
New compounds with carborane showed anti-androgen effects similar to flutamide.
research GC-MS analysis and phytochemical screening of methanolic fruit extract of Citrullus colocynthis (L.) Schrad
The methanolic fruit extract of Citrullus colocynthis contains bioactive compounds that may support its use in traditional medicine and drug development.
research Medical uses of Carthamus tinctorius L. (Safflower): a comprehensive review from Traditional Medicine to Modern Medicine
More research is needed to confirm safflower's traditional medicinal uses.
research The Case Files
The man's skin condition improved with sun protection and topical steroids, but UV exposure still caused flare-ups.
research Maculopapular rash upon antibiotic therapy in a patient with rheumatoid arthritis
Methotrexate caused a rare skin rash in a rheumatoid arthritis patient, which resolved after stopping the drug.
research Infliximab Induced Lupus in Crohnʼs Disease
Infliximab can trigger lupus-like symptoms in Crohn's disease patients.
research Liver function congruence with contraceptive medical profile in women at child-bearing ages
Long-term use of hormonal contraceptives may harm liver function.
research Alleviation of Mechanical Allodynia by 14,15-Epoxyeicosatrienoic Acid in a Central Poststroke Pain Model: Possible Role of Allopregnanolone and δ-Subunit-Containing Gamma-Aminobutyric Acid A Receptors
14,15-EET may help reduce poststroke pain by affecting certain brain proteins.
research اثر تستوسترون اگزوژن و داروی Finasteride بر بی دردی ناشی از مورفین در موش های سوری نر با استفاده از تست فرمالین
Testosterone reduces, while finasteride enhances, morphine's pain relief.
research Efficacy of Glycyrrhetinic Acid in the Treatment of Acne Vulgaris Based on Network Pharmacology and Experimental Validation
Glycyrrhetinic acid from licorice may help treat acne by reducing inflammation and oil production.
research Using 5 alpha reductase inhibitors safely: What primary care physicians need to know
5 alpha reductase inhibitors can cause sexual, cognitive, and muscle side effects, and may slightly increase aggressive cancer risk.
research Embryo‐Fetal Developmental Toxicity and Toxicokinetics Studies of YWS1903 , a Novel Potassium‐Competitive Acid Blocker, in Pregnant Rats
YWS1903 is safe for pregnant rats at moderate doses but causes fetal issues at high doses.