47 citations
,
January 2021 in “Fertility and Sterility” COVID-19 might affect male fertility, but more research is needed to understand the full impact.
January 2005 in “The Chinese Journal of Dermatovenereology” High fluoride increases damage in hair follicles, but low selenium can reduce this damage at lower fluoride levels.
Finasteride significantly reduced sperm production and caused testicular atrophy in hamsters.
36 citations
,
September 2015 in “Forensic Science International: Genetics” Certain DNA variants can predict straight hair in Europeans but are not highly specific.
January 2018 in “Genetic engineering & biotechnology news” A genetic mutation linked to longer life and less disease was found in the Amish, and a drug is being developed to replicate these benefits.
1 citations
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January 2011 in “Journal of Human Reproductive Sciences” Finasteride may decrease semen quality but not harm sperm production, and stopping the drug can improve semen quality; hyperprolactinemia can cause infertility but is treatable with medication.
6 citations
,
November 2018 in “Journal of molecular histology” Testosterone increases fluid secretion and aquaporin expression in the vas deferens, which is important for male fertility.
January 2002 in “映像情報メディア学会技術報告” Some prostate cancers have gene changes that may affect treatment with certain drugs.
May 2024 in “LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)” Certain gene combinations may affect prostate cancer risk, and GSTP1 methylation is linked to tumor aggressiveness.
4 citations
,
January 2006 in “PubMed” DHT deficiency may disrupt rat epididymis function by affecting estrogen receptors.
October 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” A small BOTOX dose improved sperm production and movement in older mice.
12 citations
,
January 1998 in “Endocrine journal” Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.
May 2023 in “Frontiers in Veterinary Science” Advancements in reproductive technologies for carnivores help conserve species and offer insights into human reproductive issues.
January 2022 in “Kafkas Universitesi Veteriner Fakultesi Dergisi” The research improved understanding of twin births and fertility in Tibetan sheep, helping animal farming.
June 2021 in “Archives of Advances in Biosciences” Finasteride reduces sperm count and quality and alters hormone levels in mice.
April 2020 in “The FASEB Journal” Finasteride may cause lasting sexual issues by altering specific genes in human cells.
10 citations
,
February 2019 in “Toxicological Sciences” Finasteride exposure affects gene expression and anogenital distance in male rat fetuses.
January 2013 in “University Libraries (University of Maryland)” Selenium helps protect cells from aging and damage, especially under stress.
January 2023 in “Advanced Biology” DNA methylation changes affect gene expression during esophageal healing with silk grafts in rats.
15 citations
,
February 1999 in “The anatomical record” Some mutant mice have hair with abnormal cross-linking, mainly in the cuticle, not affecting other hair parts.
403 citations
,
December 2018 in “Cell stem cell” Understanding phenotypic plasticity is crucial for developing effective cancer therapies.
393 citations
,
November 2000 in “Archives of General Psychiatry” Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.
349 citations
,
January 2005 in “The FASEB journal” Human skin can make serotonin and melatonin, which help protect and maintain it.
295 citations
,
September 2006 in “Cell Cycle” The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.
220 citations
,
March 2020 in “Advanced functional materials” Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.
207 citations
,
April 2006 in “Journal of The American Academy of Dermatology” Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.
174 citations
,
November 2016 in “Cell stem cell” Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.
172 citations
,
November 1983 in “Journal of The American Academy of Dermatology” Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.
168 citations
,
December 1986 in “Cancer Chemotherapy and Pharmacology” Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.
159 citations
,
September 2001 in “European Journal of Cancer Care” Chemotherapy-induced hair loss significantly affects patients' well-being, and nurses are key in helping them cope, but more research is needed to find effective treatments.