research Generation of Tβ4 knock-in Cashmere goat using CRISPR/Cas9
Researchers used CRISPR/Cas9 to create a goat with a gene that increased cashmere production by 74.5% without affecting quality.
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research ADM Scaffolds Generate a Pro-regenerative Microenvironment During Full-Thickness Cutaneous Wound Healing Through M2 Macrophage Polarization via Lamtor1
ADM scaffolds help skin heal by promoting a healing-type immune response.
research "You Need a Makeover!": The Social Construction of Female Body Image in "A Makeover Story", W"hat Not to Wear", and "Extreme Makeover"
Makeover TV shows promote unrealistic beauty standards and suggest women's worth is based on looks.
research Synthesis and biological evaluation of novel unsaturated carboxysteroids as human 5α-reductase inhibitors: A legitimate approach
New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.
research Fluridil, a Rationally Designed Topical Agent for Androgenetic Alopecia: First Clinical Experience
Fluridil safely promotes hair growth in men with androgenetic alopecia.
research Engineering Cell‐Derived Matrices: From 3D Models to Advanced Personalized Therapies
3D cell-derived matrices improve tissue regeneration and disease modeling.
research Oxidative Modification in Human Hair: The Effect of the Levels of Cu (II) Ions, UV Exposure and Hair Pigmentation
Reducing copper (II) ion levels in hair can decrease hair damage.
research Congenital adrenal hyperplasia
CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.
research Understanding Microemulsions and Nanoemulsions in (Trans)Dermal Delivery
Microemulsions and nanoemulsions can effectively deliver drugs through the skin, but more research is needed to understand their differences and mechanisms.
research Understanding the Acceptability of Subdermal Implants as a Possible New HIV Prevention Method: Multi-Stage Mixed Methods Study
PrEP implants are promising for HIV prevention if the number of implants needed is minimized.
research Bioactive Compounds from the Roots of Asiasarum heterotropoides
Two compounds from Asiasarum heterotropoides roots show potential as lung cancer treatments without harming normal cells.
research Label-free multiphoton imaging to assess neoadjuvant therapy responses in breast carcinoma
Multiphoton microscopy can effectively assess breast cancer treatment responses without labels.
research Body image and mental health in women with polycystic ovary syndrome–a cross-sectional study
Obesity and negative body image harm mental health and quality of life in women with PCOS.
research Regulation of Semaphorin3A in the process of cutaneous wound healing
Sema3A can both slow and speed up wound healing, depending on its form and combination with EGF.
research Chi-miR-30b-5p inhibits dermal papilla cells proliferation by targeting CaMKIIδ gene in cashmere goat
A specific microRNA, chi-miR-30b-5p, slows down the growth of hair-related cells by affecting the CaMKIIδ gene in cashmere goats.
research Dermatologic care of sexual and gender minority/LGBTQIA youth, Part 2: Recognition and management of the unique dermatologic needs of SGM adolescents
Pediatric dermatologists need to understand the unique skin health needs of LGBTQIA youth to provide better care.
research Finasteride and androgenic alopecia; from therapeutic options to medical implications
Finasteride can treat hair loss, but may have side effects; evaluate and inform patients of risks.
research Structure optimization of tetrahydropyridoindole-based aldose reductase inhibitors improved their efficacy and selectivity
Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.
research Comprehensive Spectroscopic Characterization of Finasteride Polymorphic Forms. Does the Form X Exist?
Three finasteride forms exist; "form X" doesn't.
research The current state of play in the histopathologic assessment of alopecia: two for one or one for two?
The document concludes that choosing the right biopsy site is crucial for accurate alopecia diagnosis, and combining methods can improve results.
research Extracellular proteoglycan decorin maintains human hair follicle stem cells
Decorin helps keep hair follicle stem cells and may prevent age-related hair loss.
research A Spontaneous Deletion within the Desmoglein 3 Extracellular Domain of Mice Results in Hypomorphic Protein Expression, Immunodeficiency, and a Wasting Disease Phenotype
A gene deletion in mice causes weak protein, immune issues, hair loss, airway problems, and wasting disease.
research Different Requirements for GFRα2-Signaling in Three Populations of Cutaneous Sensory Neurons
GFRα2 is essential for controlling neuron size but not for target innervation in certain sensory neurons.
research Self‐concept and body image of people living with lupus: A systematic review
Lupus patients' body image issues significantly affect their mental health and need more support.
research Facial preservation following extreme mummification: Shrunken heads
Shrunken heads retain some facial features and hair characteristics, allowing for limited individual identification.
research A study on the conditioning effects of natural shampoos using the scanning electron microscope*
Natural shampoos made in the lab conditioned hair better than commercial ones with chemicals.
research A doxycycline- and light-inducible Cre recombinase mouse model for optogenetic genome editing
The DiLiCre mouse model is an effective tool for precise genome editing using light.
research Development of Novel Indole-Based Bifunctional Aldose Reductase Inhibitors/Antioxidants as Promising Drugs for the Treatment of Diabetic Complications
New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.
research Intrinsic activation of cell growth and differentiation in ex vivo cultured human hair follicles by a transient endogenous production of ROS
Temporary ROS production in cultured human hair follicles promotes growth and stem cell activation.
research Organic and Psychogenic Causes of Sexual Dysfunction in Young Men
Young men's sexual dysfunction often has physical causes, which can lead to stress and worsen the problem.