13 citations
,
July 2022 in “Frontiers in cell and developmental biology” Tiny natural vesicles from cells might help treat hair loss.
9 citations
,
January 2018 in “Stem Cells International” Deer antler stem cell fluid helps regenerate tissue better than fat-derived stem cell fluid.
5 citations
,
March 2019 in “Scientific Reports” The technique can isolate cells to help treat skin pigmentation issues.
January 2025 in “American Journal of Stem Cells” Melanocyte stem cells hold promise for skin regeneration and treating pigmentation issues.
245 citations
,
January 2018 in “Bone Research” TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
202 citations
,
August 2017 in “Nature cell biology” Lactate production is important for activating hair growth stem cells.
80 citations
,
April 2018 in “Trends in Molecular Medicine” Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.
71 citations
,
January 2015 in “Journal of molecular cell biology/Journal of Molecular Cell Biology” mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.
23 citations
,
August 2018 in “Facial Plastic Surgery Clinics of North America” Using defensins to activate stem cells may improve skin aging signs without causing inflammation.
19 citations
,
July 2011 in “Microscopy and Microanalysis” The hair follicle bulge is an important area for adult stem cells involved in hair growth and repair, with potential for medical use needing more research.
14 citations
,
July 2016 in “Anatomical Science International” The study suggests that the arrector pili muscle is important for hair health and its damage might contribute to hair loss.
11 citations
,
May 2015 in “Stem Cells Translational Medicine” Megestrol acetate helps fat-derived stem cells grow, move, and turn into fat cells through a specific receptor.
6 citations
,
July 2023 in “Nature cell biology” SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.
September 2023 in “Nature communications” Alk1 in specific cells is crucial for proper nerve branching and hair function.
9 citations
,
January 2022 in “Theranostics” Collagen XVII is important for skin aging and wound healing.
11 citations
,
December 2018 in “Bone” Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.
408 citations
,
January 2017 in “Science” Some wound-healing cells can turn into fat cells around new hair growth in mice.
242 citations
,
February 2016 in “Science” Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.
165 citations
,
June 2007 in “European Journal of Cell Biology” Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
65 citations
,
April 2020 in “International Journal of Molecular Sciences” PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.
64 citations
,
December 2012 in “Stem Cell Reviews and Reports” Human hair follicle cells can be turned into stem cells similar to embryonic stem cells.
46 citations
,
June 2015 in “Journal of Investigative Dermatology” Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
43 citations
,
January 2011 in “Plastic and Reconstructive Surgery” Stem cells have great potential for improving wound healing, but more research is needed to find the best types and ways to use them.
40 citations
,
April 2014 in “Genes & Development” Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.
36 citations
,
September 2013 in “PLoS ONE” Sweat gland stem cells help maintain glands, aid wound healing, and can regenerate skin structures.
28 citations
,
January 2013 in “Stem cells” Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.
18 citations
,
November 2020 in “Frontiers in Cell and Developmental Biology” Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
16 citations
,
January 2007 in “Dermatology” Scientists have made progress in understanding hair follicle stem cells, identifying specific genes and markers, and suggesting their use in treating hair and skin conditions.
15 citations
,
February 2021 in “Scientific Reports” A specific group of stem cells can help regenerate hair continuously.
April 2026 in “Experimental & Molecular Medicine” Mouse and human skin development share similar fibroblast timelines.