721 citations
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October 2011 in “Nature” Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.
501 citations
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October 2008 in “Psychoneuroendocrinology” Hair cortisol levels can show increased stress during late pregnancy but only for up to six months.
418 citations
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September 2012 in “Nature” African spiny mice can regenerate skin, hair, and cartilage, but not muscle, and their unique abilities could be useful for regenerative medicine.
417 citations
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March 1991 in “American Journal of Psychiatry” Most adult chronic hair pullers are women who started in their early teens, often have other mental health issues, and may pull hair due to underlying psychiatric conditions.
316 citations
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June 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.
301 citations
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February 2019 in “Nature Communications” The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.
214 citations
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March 1993 in “Archives of Dermatology” Telogen effluvium is a reversible hair loss condition that requires a detailed diagnosis and often resolves on its own.
205 citations
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March 2012 in “Science Translational Medicine” PGD2 stops hair growth and is higher in bald men with AGA.
193 citations
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August 1985 in “Endocrinology” Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.
192 citations
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March 2017 in “Cell host & microbe” Hair follicle development and microbes help regulatory T cells gather in newborn skin.
133 citations
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February 2019 in “PLoS Biology” Feather patterns in birds are shaped by signaling interactions and cell movements, with EDA/EDAR crucial for pattern formation.
130 citations
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January 2017 in “International journal of nanomedicine” Silver nanoparticles coated with substances like PEG showed strong antibacterial effects and improved wound healing when used in hydrogels.
124 citations
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June 2020 in “Cell Stem Cell” Fat cells in the skin help start healing and form important repair cells after injury.
117 citations
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March 2017 in “Nature Communications” Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.
116 citations
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September 2020 in “Nature Communications” The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.
115 citations
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November 1999 in “Journal of The American Academy of Dermatology” Minoxidil increases hair weight and count temporarily in men with hair loss.
113 citations
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April 1999 in “The Journal of Clinical Endocrinology and Metabolism” Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.
109 citations
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December 2003 in “American Journal of Pathology” Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.
96 citations
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September 2017 in “Analytica Chimica Acta” Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.
95 citations
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July 2010 in “Genes & development” Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.
92 citations
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August 2017 in “Proceedings of the National Academy of Sciences of the United States of America” Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.
86 citations
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April 2016 in “Nature Communications” Notch1 helps skin heal by attracting specific immune cells.
85 citations
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December 1990 in “Journal of Investigative Dermatology” Minoxidil promotes hair growth in women with early-stage alopecia.
84 citations
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July 2008 in “Aaps Pharmscitech” Ethosomes improve finasteride delivery through skin for hair loss treatment.
82 citations
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January 2002 in “Journal of drug targeting” Drugs penetrate scalp skin better than abdominal skin, with scalp hair follicles aiding in higher drug delivery.
82 citations
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March 1994 in “Archives of Dermatology” 2% topical minoxidil effectively treats female hair loss with minimal side effects.
80 citations
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June 2008 in “Biomaterials” EVAL membranes help create cell structures that can regrow hair follicles.
78 citations
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May 1989 in “The Journal of Clinical Endocrinology & Metabolism” Spironolactone effectively reduces hair growth in women with hirsutism and is generally well-tolerated.
76 citations
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December 2006 in “Journal of Dermatological Science” Japanese women typically start experiencing hair loss after 40, with reduced hair density and thickness being the main factors.
72 citations
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December 1996 in “Journal of Investigative Dermatology” Human hair follicles can regenerate after removal, but with low success rate.