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5α-reductase affects dopamine receptors linked to sensorimotor gating, which may help understand disorders like schizophrenia.

Different mutations in the 5 alpha-reductase-2 gene were found in affected individuals in the Dominican Republic, suggesting no common ancestry.

Finasteride effectively inhibits the enzyme steroid 5 alpha-reductase II.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

S-1 treatment led to a complete response in pancreatic cancer with manageable side effects.

A new mouse mutation causes skin and hair defects due to a gene change.

RAR-gamma 1 is important for normal skin maintenance and differentiation.

MK-0773 is a moderate inhibitor of the SRD5A2 enzyme.

About 50% of 46, XY DSD cases lack a genetic diagnosis, but advanced sequencing methods improve detection.

5 Alpha-Reductase Inhibitors reduce the effects of testosterone by blocking its conversion into a stronger form.

Recombinant Human Annexin A5 may help treat localized scleroderma by reducing skin thickening and inflammation.

The research helps understand how finasteride works and aids drug development.

SRD5A2 enzyme expression varies in benign prostates and can be influenced by inflammation, affecting treatment options.

Scientists made a sensor that can detect a specific type of RNA related to androgen receptors quickly and accurately.

5-ARI therapy may help prevent prostate cancer progression.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

A new genetic mutation linked to CARASIL syndrome and small artery disease was found in a Chinese family.

The P133R mutation in AKR1D1 enzyme causes harmful bile acid buildup, explaining related health issues.

AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

Biochanin A from soy is a promising and safe candidate for treating hair loss.

Biochanin A from soy is a promising and safe candidate for treating hair loss.

SIG-1451 could be a promising new treatment for atopic dermatitis.

Circ-Smad5 slows cell growth by blocking a specific cell signaling pathway.

Blocking certain receptors in the lungs might help treat a specific type of asthma.

SARMs may offer benefits by boosting muscle effects without unwanted side effects.

The new ddPCR method reliably detects unwanted viruses in CAR-T cell products, ensuring their safety for patients.

ARL15 is important for fat cell development and the release of the hormone adiponectin.

Using hair loss drugs finasteride and dutasteride may cause sexual side effects.