72 citations
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January 2012 in “Annals of Dermatology” IGF-I promotes hair growth by keeping hair follicles in the growth phase longer.
71 citations
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November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Edar signaling is crucial for proper hair follicle development and function.
70 citations
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January 2014 in “International review of cell and molecular biology” Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
67 citations
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August 2013 in “International Journal of Cosmetic Science” Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.
60 citations
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July 2014 in “Autophagy” The protein FLCN is involved in cellular cleanup and is regulated by ULK1.
59 citations
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February 1998 in “Chemico-Biological Interactions” Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.
58 citations
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November 2020 in “International Journal of Molecular Sciences” SHBG may be a useful early indicator and treatment target for PCOS.
58 citations
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January 2003 in “Biological & Pharmaceutical Bulletin” Bombax ceiba stem bark extracts can lower blood pressure, but high doses can be toxic and lethal.
52 citations
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August 2021 in “Microorganisms” Higher ACE2 levels in certain tissues may worsen COVID-19 in people with other health issues, especially older adults.
51 citations
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July 2010 in “Trends in Endocrinology and Metabolism” Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.
49 citations
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September 2008 in “International journal of pharmaceutics” Artificial sebum L closely mimics human sebum for drug delivery research.
47 citations
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May 2021 in “Polymers” Jojoba oil is highly valued for its diverse medicinal and industrial uses.
46 citations
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February 2016 in “Experimental Dermatology” Genes play a significant role in male-pattern baldness, and understanding them could lead to new treatments and insights into related health issues.
46 citations
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May 2003 in “Mechanisms of Development” Increasing calcium sensing receptor speeds up skin and hair development in mice.
45 citations
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July 2022 in “Frontiers in Pharmacology” Natural products can help heal wounds by affecting key biological pathways.
44 citations
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March 2004 in “Journal of Investigative Dermatology” The effects of estrogen on human hair growth are unclear and need more research.
41 citations
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October 2019 in “Biomolecules” Retinoic acid can either maintain stem cells or make them specialize, depending on the cell type.
40 citations
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December 2012 in “PLoS ONE” Removing Ctip2 in skin cells causes skin inflammation similar to atopic dermatitis.
37 citations
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April 2011 in “Journal of Biological Chemistry” LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.
36 citations
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October 2007 in “Journal of Investigative Dermatology” Betacellulin helps blood vessel growth in wounds but delays hair growth.
35 citations
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July 2015 in “Journal of Affective Disorders” Women with PCOS tend to have higher anxiety and depression levels compared to healthy women.
35 citations
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March 2014 in “British Journal of Dermatology” Hair loss in male pattern baldness involves muscle degeneration and increased scalp fat.
35 citations
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January 2011 in “Journal of Biological Chemistry” sPLA2-X is crucial for normal hair growth and follicle health.
35 citations
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September 2009 in “Development” Necl2 affects skin cell behavior and slows wound healing.
35 citations
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January 2004 in “European journal of oncology nursing” Capecitabine is as effective as intravenous treatments with fewer side effects, but requires careful management of Hand-foot syndrome and patient education.
32 citations
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September 2018 in “Journal of pharmaceutical sciences” The model better predicts how water-loving and fat-loving substances move through the skin by including tiny pores and hair follicle paths.
32 citations
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August 2015 in “Journal of Investigative Dermatology” Prominin-1 expressing cells in the dermal papilla help regulate hair follicle size and communication but don't aid in skin repair.
31 citations
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May 2019 in “Nature communications” Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.
31 citations
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September 2012 in “Journal of biological chemistry/The Journal of biological chemistry” The right amount of retinoic acid is essential for normal hair growth and development.
30 citations
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June 2024 in “Scientific Reports” The hydrogel shows promise for wound healing due to its strong mechanical, antimicrobial, and antioxidant properties.