50 citations
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November 2015 in “Journal of pharmacological sciences” α-mangostin nanoparticles improved acne with minimal irritation.
34 citations
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January 2005 in “Journal of the American Veterinary Medical Association” Cyclosporine A can reduce inflammation in dogs with sebaceous adenitis, but ongoing treatment is needed.
29 citations
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February 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Loss of Fz6 disrupts hair follicle and associated structures' orientation.
28 citations
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July 2008 in “Developmental Biology” Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.
25 citations
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June 2011 in “International journal of pharmaceutics” Nanoparticles effectively deliver water-insoluble drugs to hair follicles, stimulating hair growth without irritating the skin.
21 citations
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May 2014 in “Toxicological Sciences” Toluene diisocyanate exposure can cause immune sensitization by interacting with proteins in hair follicles and sebaceous glands.
18 citations
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August 2015 in “International Journal of Molecular Sciences” Ovine hair follicle stem cells can regenerate haired skin and may improve wool production.
14 citations
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January 2021 in “Stem cell research & therapy” Human skin cells with stem-like features can help create new hair follicles and sebaceous glands when combined with other cells.
14 citations
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October 2018 in “PloS one” Deleting the Far2 gene in mice causes sebaceous gland issues and patchy hair loss.
5 citations
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April 2021 in “Biomedicines” The engineered skin substitute helped grow skin with hair on mice.
4 citations
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January 2017 in “PubMed” Epidermal growth factor helps stem cells heal wounds and regenerate hair follicles faster.
2 citations
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October 2015 in “Indian journal of science and technology” SM-215 promotes hair growth by improving the environment around hair follicles.
1 citations
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September 2022 in “Biomaterials advances” 3D bioprinting can effectively regenerate hair follicles and skin tissue in wounds.
1 citations
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July 2005 in “Informa Healthcare eBooks” Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.
1 citations
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January 2001 in “Journal of Toxicology-cutaneous and Ocular Toxicology” Hair follicles could be used to deliver drugs effectively, with the right understanding and methods.
1 citations
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October 2021 in “Gene, cell and tissue” Grape sap may help reduce hair loss and promote hair growth in rats.
January 2019 in “Journal of Entomology and Zoology Studies” Ruminant goats have larger and more defined hair follicles than younger goats.
April 2015 in “The FASEB Journal” Nitrogen mustard causes DNA damage and structural changes in mouse skin hair follicles, but some recovery occurs after 5 days.
Antiandrogen treatment helps reduce hair follicles and sebaceous glands in hirsute women.
January 2013 in “Journal of Tissue Engineering and Reconstructive Surgery” Inserting hair follicle units improved the development of tissue-engineered skin.
352 citations
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August 2003 in “Proceedings of the National Academy of Sciences” Nestin is found in hair follicle progenitor cells, linking them to neural stem cells.
335 citations
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March 2004 in “Development” Temporary activation of β-catenin can create new hair follicles, but ongoing activation is needed to keep hair follicle tumors.
297 citations
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January 2002 in “Development” Overexpression of ΔNLef1 in mouse skin leads to hair loss, cysts, and skin tumors.
165 citations
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June 2007 in “European Journal of Cell Biology” Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
146 citations
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May 2002 in “The American journal of pathology” Cathepsin L is essential for normal hair growth and development.
86 citations
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December 2001 in “Experimental dermatology” Mutant mice help researchers understand hair growth and related genetic factors.
73 citations
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June 2001 in “Endocrinology” Prolactin affects when mice shed and grow hair.
71 citations
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November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Edar signaling is crucial for proper hair follicle development and function.
71 citations
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June 2005 in “Journal of Investigative Dermatology” PAD enzymes play a key role in hair growth and structure.
65 citations
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September 2004 in “The American journal of pathology” Blocking BMP signaling causes hair loss and disrupts hair growth cycles.