421 citations
,
September 2003 in “Development” Stem cell behavior varies with stimuli, and lineage changes can happen without affecting stem cell division.
335 citations
,
March 2004 in “Development” Temporary activation of β-catenin can create new hair follicles, but ongoing activation is needed to keep hair follicle tumors.
169 citations
,
June 2013 in “Medicine” Understanding skin's structure and function is crucial for grasping skin health and diseases.
143 citations
,
October 1988 in “Clinics in Dermatology” The understanding of male-pattern baldness remains unclear.
142 citations
,
January 2010 in “Journal of dermatological science” Hair follicles are promising targets for delivering drugs effectively.
139 citations
,
August 2006 in “Molecular and Cellular Biology” Rac1 is vital for hair follicle health but not needed for skin maintenance.
101 citations
,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists turned mouse stem cells into skin cells that can grow into skin layers and structures.
82 citations
,
January 1994 in “Skin Pharmacology and Physiology” Hair follicles and glands significantly increase steroid absorption in skin.
80 citations
,
June 2012 in “European Journal of Pharmaceutics and Biopharmaceutics” Nanoparticles improve drug delivery and effectiveness in treating inflamed skin.
80 citations
,
January 1995 in “The American Journal of Medicine” Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.
78 citations
,
June 1989 in “The Journal of dermatologic surgery and oncology” Acne keloidalis is a chronic skin condition on the back of the neck in young black men, needing surgery for severe cases.
77 citations
,
May 2017 in “Medicine” Understanding skin structure and function is crucial for grasping skin health and diseases.
71 citations
,
June 2005 in “Journal of Investigative Dermatology” PAD enzymes play a key role in hair growth and structure.
68 citations
,
May 2009 in “Medicine” Understanding skin structure and function is crucial due to its role in health and prevalence of many skin diseases.
63 citations
,
July 2006 in “British Journal of Dermatology” Psoriasis causes changes in certain keratins and shrinks sebaceous glands in the scalp.
60 citations
,
August 1969 in “British Journal of Dermatology” Germicides mostly stay on the skin's surface, but some penetrate deeper depending on the product used.
56 citations
,
July 2005 in “Experimental Dermatology” Injected human hair follicle cells can create new, small hair follicles in skin cultures.
47 citations
,
January 1998 in “Molecular Carcinogenesis” ErbB2 signaling is crucial for skin cell growth and cancer development in mice.
45 citations
,
August 1954 in “Experimental Biology and Medicine” Vitamin A penetrates guinea pig skin quickly in alcohol, affects skin thickness, but doesn't impact hair growth.
40 citations
,
May 2012 in “British Journal of Dermatology” Recognizing specific features of African-American hair can help diagnose hair loss conditions.
39 citations
,
June 2018 in “Burns” The spiny mouse can fully regenerate skin after burns, unlike the lab mouse.
39 citations
,
January 2016 in “PubMed” Understanding how EDC genes are regulated can help develop better drugs for skin diseases.
39 citations
,
July 2015 in “British Journal of Dermatology” The pseudo 'fringe sign' can also appear in frontal fibrosing alopecia, not just in traction alopecia, showing that this condition may be more common than thought.
37 citations
,
January 1997 in “Journal of Pharmaceutical Sciences” Hairless rats absorb substances through their skin more easily than hairy rats.
37 citations
,
April 1977 in “Journal of Cutaneous Pathology” Skin biopsy can help diagnose hair loss from trichotillomania.
28 citations
,
October 2024 in “Advanced Materials” Artificial skin can heal wounds without scars and regenerate hair, oil, and sweat glands.
27 citations
,
August 2016 Understanding skin structure and function is key to managing skin diseases and improving quality of life.
27 citations
,
July 1997 in “PubMed” The harlequin ichthyosis mouse mutation causes thick skin and early death, resembling a human skin disorder.
25 citations
,
November 2015 in “Journal of Dermatological Science” Sebum helps protect human skin from microbes.
24 citations
,
January 2019 in “Biomaterials Science” The shape of fibrous scaffolds can improve how stem cells help heal skin.