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The role of γδT-cells in causing alopecia areata remains unclear.

The BMP/Smads pathway and Id2 gene control hair follicle stem cells, affecting their rest and growth phases.

Triptolide effectively and safely reduces actinic keratosis lesions in mice.

Scientists created a tiny, 3D model of a hair follicle that grows and acts like a real one.

A boy with Oculodentodigital syndrome had a unique GJA1 gene mutation causing his symptoms.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

Human hair follicle stem cells show signs of low oxygen levels, which may be important for hair growth and preventing baldness.

Hair follicles on the scalp interact with and respond to the nervous system, influencing their own behavior and growth.

Parathyroid hormones are important for hair growth, but their use in treating hair loss from chemotherapy is still uncertain.

Mice with too much sPLA₂-IIA have hair loss and poor wound healing due to abnormal hair growth and stem cell depletion.

Anti-androgens are safe and effective for treating moderate to severe adult female acne.

Old drugs like finasteride and spironolactone are being successfully used for hair loss and skin conditions, and many other drugs show promise for new uses in dermatology.

Hormones, especially androgens, play a key role in causing acne, and treatments like hormone control pills and hormone-blocking medications can help.

Birth control pills help treat acne, especially when caused by excess male hormones, and are safe to use with antibiotics.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Estrogen therapy can reduce skin aging but has cancer risks.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.