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In Vivo and In Vitro Exposure to Free Fatty Acids Induce Increased Androgen Production in Animal Models: A Potential Pathogenic Factor of Polycystic Ovary Syndrome

research In vivo and in vitro exposure to free fatty acids induce increased androgen production in animal models: a potential pathogenic factor of the polycystic ovary syndrome

September 2008 in “Fertility and Sterility”

Free fatty acids may increase androgen production, potentially contributing to polycystic ovary syndrome.

research Overexpression of HE4/WFDC2 gene in mice leads to keratitis and corneal opacity

January 2025 in “Open Life Sciences”

Overexpression of the HE4 gene in mice causes eye inflammation and cloudiness.

research A comparison between spironolactone and spironolactone plus finasteride in the treatment of hirsutism

47 citations , March 2004 in “European journal of endocrinology”

Spironolactone plus finasteride reduces hirsutism more effectively.

research SAT-510 Association of Myotonic Dystrophy with Autoimmune Endocrinopathies and Thyroid Carcinoma

April 2020 in “Journal of the Endocrine Society”

A patient with myotonic dystrophy had several autoimmune disorders and thyroid cancer, suggesting a possible link between these conditions.

research 1424 Mapping the establishment of fibroblast heterogeneity during skin development and wound repair

April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

Skin heals with scars because only one type of fibroblast is used, not a mix.

research Obesity and the skin: Skin physiology and skin manifestations of obesity

405 citations , May 2007 in “Journal of The American Academy of Dermatology”

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

research Is dehydroepiandrosterone a hormone?

403 citations , November 2005 in “Journal of Endocrinology”

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Sex Steroid Synthesis in Human Skin In Situ: The Roles of Aromatase and Steroidogenic Acute Regulatory Protein in the Homeostasis of Human Skin

research Sex steroid synthesis in human skin in situ: The roles of aromatase and steroidogenic acute regulatory protein in the homeostasis of human skin

46 citations , May 2012 in “Molecular and Cellular Endocrinology”

Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.

Spironolactone Versus Placebo or in Combination with Steroids for Hirsutism and Acne

research Spironolactone versus placebo or in combination with steroids for hirsutism and/or acne

32 citations , October 2003

Spironolactone is better than placebo for reducing excessive hair growth in women, but its effectiveness for acne is unclear due to small study sizes.

research Blimp1+ cells generate functional mouse sebaceous gland organoids in vitro

31 citations , May 2019 in “Nature communications”

Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.

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