research Chemotherapy of psoriasis and other skin disorders with oral retinoids
Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.
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research Pharmacologic Modulation of Sebaceous Gland Activity: Mechanisms and Clinical Applications
The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.
research Endocrine evaluation of hirsutism
Women with excessive male-pattern hair growth should get a full hormone check-up to find and treat any underlying issues, considering both medical and emotional aspects.
research Diffusion properties of model compounds in artificial sebum
Different compounds move through artificial sebum at different rates, which can help choose the best ones for targeting hair follicles.
research The Use of Photodynamic Therapy for Treatment of Acne Vulgaris
Photodynamic Therapy is an effective treatment for mild to severe acne.
research Inactivation of autophagy leads to changes in sebaceous gland morphology and function
Autophagy is crucial for normal sebaceous gland function and sebum composition.
research Pharmacological Inhibition of Stearoyl CoA Desaturase in the Skin Induces Atrophy of the Sebaceous Glands
Blocking SCD1 in the skin with XEN103 shrinks sebaceous glands in mice.
research Hormone therapy in acne
Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.
research Evaluation of New Pregnane Derivatives as 5.ALPHA.-Reductase Inhibitor.
New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.
research Ligand‐independent epidermal growth factor receptor hyperactivation increases sebaceous gland size and sebum secretion in mice
EGFR hyperactivation increases sebaceous gland size and sebum production in mice.
research Contraceptive use in acne
Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.
research Getting under the skin of hair aging: the impact of the hair follicle environment
Aging scalp skin contributes to hair aging and loss, and more research is needed to develop better hair loss treatments.
research Antiandrogen Therapy for Skin and Hair Disease
Antiandrogen therapies are beneficial for treating skin and hair conditions related to androgen levels.
research Skin and glucocorticoids: effects of local skin glucocorticoid impairment on skin homeostasis
Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.
research The effects of narrowbands of visible light upon some skin disorders: a review
Visible light can improve skin disorders and hair loss, but more research is needed to understand long-term effects.
research Cosmetic potential of Southeast Asian herbs: an overview
Southeast Asian herbs show promise for skin and hair care, but more research is needed to confirm their effectiveness in cosmetics.
research New Pharmaceutical Concepts for Sebaceous Gland Diseases: Implementing Today’s Pre-Clinical Data into Tomorrow’s Daily Clinical Practice
New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
research Sebaceous gland abnormalities in fatty acyl CoA reductase 2 (Far2) null mice result in primary cicatricial alopecia
Deleting the Far2 gene in mice causes sebaceous gland issues and patchy hair loss.
research Characterization of hair lipid images by argon sputter etching-scanning electron microscopy
Hair texture changes with age due to varying levels of lipids.
research Acne: Diet and acnegenesis
Eating dairy and high glycemic foods may increase the risk of acne.
research Transfollicular drug delivery: current perspectives
Transfollicular drug delivery is promising but needs more research to improve and understand it better.
research Androgens and acne: perspectives on clascoterone, the first topical androgen receptor antagonist
Clascoterone is a new, effective, and safe acne treatment without systemic side effects.
research Androgenetic alopecia and hair growth promotion state of the art: Present and future
Current research explores hair growth drugs, while future research aims for personalized treatments.
research Ozenoxacin suppresses sebum production by inhibiting mTORC1 activation in differentiated hamster sebocytes
Ozenoxacin reduces sebum production, helping manage acne.
research Pharmacological Inhibition of DGAT1 Induces Sebaceous Gland Atrophy in Mouse and Dog Skin While Overt Alopecia Is Restricted to the Mouse
Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.
research Possible intermediary role of ghrelin in seborrhea
The conclusion suggests that the hormone ghrelin might link acid reflux to oily skin.
research Impact of Testosterone on Hair and Skin
Testosterone can cause acne and male-pattern baldness, affects hair growth in men and women, and makes male skin more sensitive.
research Vitamin D Status Assessment: Lack of Correlation between Serum and Hair 25-Hydroxycholecalciferol Levels in Healthy Young Adults
Vitamin D levels in hair don't match those in blood, so hair isn't a reliable indicator of Vitamin D status.
research Research Progress of Skin Barrier and Acne
Impaired skin barrier function worsens acne.
research Effect of an oral probiotic formula on scalp and facial skin condition, glucose, and lipid metabolism
Taking a probiotic supplement twice a day improved hair growth, skin hydration, and metabolic health in adults at risk of metabolic syndrome.