research Roles of jumonji and jumonji family genes in chromatin regulation and development
Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.
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research Functionally distinct melanocyte populations revealed by reconstitution of hair follicles in mice
Only skin melanocytes, not other types, can color hair in mice.
research The laboratory in the multidisciplinary diagnosis of differences or disorders of sex development (DSD)
Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.
research Epidermal Development in Mammals: Key Regulators, Signals from Beneath, and Stem Cells
Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
research Hair development and Langerhans cell migration during human embryogenesis
Langerhans cells and melanocytes migrate to the skin and hair follicles during early human development.
research Identification of Key Pathways and Genes Related to the Development of Hair Follicle Cycle in Cashmere Goats
Twelve key genes may improve cashmere production by influencing hair follicle cycles.
research Melatonin’s Role in Hair Follicle Growth and Development: A Cashmere Goat Perspective
Melatonin promotes hair growth and quality by enhancing hair follicle development and reducing stress.
research Regulation of Hair Follicle Growth and Development by Different Alternative Spliceosomes of FGF5 in Rabbits
FGF5 spliceosomes inhibit rabbit hair growth by affecting gene expression.
research Status of research on the development and regeneration of hair follicles
New regenerative medicine-based therapies for hair loss look promising but need more clinical validation.
research Selenoproteins Are Essential for Proper Keratinocyte Function and Skin Development
Selenoproteins are crucial for healthy skin and hair.
research Development and Homeostasis of the Skin Epidermis
The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
research Oxidative stress in hair follicle development and hair growth: Signalling pathways, intervening mechanisms and potential of natural antioxidants
Natural antioxidants may help prevent hair loss by reducing oxidative stress.
research Betacellulin Regulates Hair Follicle Development and Hair Cycle Induction and Enhances Angiogenesis in Wounded Skin
Betacellulin helps blood vessel growth in wounds but delays hair growth.
research Over-expression of thymosin beta4 promotes abnormal tooth development and stimulation of hair growth
Too much thymosin beta4 causes weird teeth and more hair growth in mice.
research Review of Human Hair Follicle Biology: Dynamics of Niches and Stem Cell Regulation for Possible Therapeutic Hair Stimulation for Plastic Surgeons
Understanding hair follicle biology and stem cell control could lead to new hair loss treatments.
research Developmental genetics of color pattern establishment in cats
Cat color patterns are determined early in development by gene expression and epidermal changes, with the Dickkopf 4 gene playing a crucial role.
research Back to the Future: From Appendage Development Toward Future Human Hair Follicle Neogenesis
New hair follicles could be created to treat hair loss.
research Overactive Wnt5a signaling disrupts hair follicle polarity during mouse skin development
Overactive Wnt5a disrupts hair follicle orientation in mice.
research Mesenchymal stem cell‐derived exosomes for organ development and cell‐free therapy
MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.
research Ectopic Sebaceous Glands in the Hair Follicle Matrix: Case Reports and Literature Review of this Embryogenic Anomaly
The cause and importance of misplaced oil glands in the hair follicle are not well understood.
research Immunological control of skin development: from homeostasis to developmental pathologies
Immune cells are crucial for normal skin development and their dysfunction can cause skin disorders.
research Progress on mitochondria and hair follicle development in androgenetic alopecia: relationships and therapeutic perspectives
Maintaining healthy mitochondria may help treat hair loss.
research A Window into Mammalian Basement Membrane Development: Insights from themTurq2-Col4a1Mouse Model
The mTurq2-Col4a1 mouse model shows that cells can divide while attached to stable basement membranes during development.
research K15 promoter-driven enforced expression of NKIRAS exhibits tumor suppressive activity against the development of DMBA/TPA-induced skin tumors
NKIRAS2 can suppress certain skin tumors but its effect on cancer varies with context and expression level.
research CD34 Expression by Hair Follicle Stem Cells Is Required for Skin Tumor Development in Mice
CD34 is crucial for skin tumor development in mice.
research MmuPV1 infection and tumor development of T cell-deficient mice is prevented by passively transferred hyperimmune sera from normal congenic mice immunized with MmuPV1 virus-like particles (VLPs)
Giving immune serum from vaccinated mice to mice without T cells prevents infection and tumor growth.
research Pannexin 3 regulates skin development via Epiprofin
Pannexin 3 helps skin and hair growth by controlling a protein called Epiprofin.
research Development and Evaluation of a Niosome-Integrated Microneedle System for Targeted Follicular Delivery of Ketoconazole in Alopecia Therapy
The new microneedle system improves hair growth in alopecia treatment.
research 1424 Mapping the establishment of fibroblast heterogeneity during skin development and wound repair
Skin heals with scars because only one type of fibroblast is used, not a mix.
research Developmental Mechanisms Controlling Cell Fate, Evolution of
The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.