research Hyperprogesteronismus infolge bilateraler Nebennierenrindenkarzinome bei einer Katze mit Diabetes mellitus
Adrenal tumors can cause high progesterone levels, mimicking symptoms of high cortisol.
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research Co-secretion of testosterone and cortisol by a functional adrenocortical oncocytoma
A woman's rare adrenal tumor caused high testosterone and cortisol levels, which normalized after the tumor was removed.
research Immune Cells in Cutaneous Wound Healing: A Review of Functional Data from Animal Models
Different immune cells like platelets, mast cells, neutrophils, macrophages, T cells, B cells, and innate lymphoid cells all play roles in skin wound healing, but more research is needed due to inconsistent results and the complex nature of the immune response.
research Thermodynamically stable ionic liquid microemulsions pioneer pathways for topical delivery and peptide application
New method improves copper peptide delivery for hair growth three times better than current options.
research Cross-Signaling Between Hair Follicle Stem Cells And Dermal Lymphatic Vessels: A Systematic Review
This systematic review explores the interactions between hair follicle stem cells (HFSCs) and dermal lymphatic vessels, highlighting their role in hair growth and tissue regeneration. The review includes 10 studies, mostly in murine models, and reveals that HFSCs and lymphatic vessels engage in dynamic cross-signaling throughout the hair cycle. During the anagen phase, lymphatic vessels dilate and enhance fluid drainage, while HFSCs secrete Angptl7 in the telogen phase to maintain lymphatic function. Lymphatic endothelial cells (LECs) promote HFSC growth by secreting growth signals like IGF-1 and Sostdc1, which activate Wnt signaling. Enhanced lymphangiogenesis prolongs hair growth, whereas LEC depletion leads to hair follicle regression. A human study links aging and alopecia with reduced lymphatic networks. The findings suggest that targeting HFSC-lymphatic signaling could offer new therapeutic avenues for hair loss and wound healing.
research Cross-Signaling Between Hair Follicle Stem Cells And Dermal Lymphatic Vessels: A Systematic Review
This systematic review explores the interactions between hair follicle stem cells (HFSCs) and dermal lymphatic vessels, highlighting their role in hair growth and tissue regeneration. The review includes 10 studies, mostly in murine models, and reveals that HFSCs and lymphatic vessels engage in dynamic cross-signaling throughout the hair cycle. During the anagen phase, lymphatic vessels dilate and enhance fluid drainage, while HFSCs secrete Angptl7 in the telogen phase to maintain lymphatic function. Lymphatic endothelial cells (LECs) promote HFSC growth by secreting growth signals like IGF-1 and Sostdc1, which activate Wnt signaling. Enhanced lymphangiogenesis prolongs hair growth, whereas LEC depletion leads to hair follicle regression. A human study links aging and alopecia with reduced lymphatic networks. The findings suggest that targeting HFSC-lymphatic signaling could offer new therapeutic avenues for hair loss and wound healing.
research Establishment and identification of immortalized sheep ovarian granulosa cells
A stable sheep ovarian cell line was created for studying reproduction and hormones.
research 0855 Topological laser delivery induces efficient regeneration via a transient cell network with super activation of hepatocyte growth factor
Laser treatment boosts hair growth by activating a key growth factor.
research AORTOCAVAL PARAGANGLIOMA IN VON HIPPEL-LINDAU DISEASE
VHL disease can cause early paragangliomas, needing lifelong monitoring.
research A brief report on PCOS: and its inducing model
PCOS causes hormonal imbalance, leading to symptoms like irregular periods and infertility.
research A Large Benign Adrenocortical Adenoma Cosecreting Testosterone and Cortisol
A woman's rare benign tumor that released both cortisol and testosterone was successfully removed, improving her health.
research Higher percentage of CD34 + stem cells and elevated efficacy in androgenetic alopecia treatment observed in CGF prepared from 640 nm laser‐pretreated blood: A preliminary study
Laser-pretreated blood for hair loss treatment was more effective and increased stem cells.
research 1407 Mechanical force activation of TGF-β signaling controls hair follicle regression
Muscle around hair follicles controls hair loss by releasing a signal that causes cell death.
research MON-913 Testosterone Secreting Ovarian Tumor: A Rare Cause of Erythrocytosis and Pulmonary Embolus
A rare ovarian tumor that produced testosterone caused a blood clot in the lungs and increased red blood cells in a woman.
research Female Progressive Scalp Hair Loss Associated with Ovarian Thecoma
A woman's hair loss was linked to a rare hormone-secreting ovarian tumor, treated with surgery and hair loss medication.
research Hyperinsulinism, Insulin Resistance and Fertility
Insulin resistance and hyperinsulinism are linked to fertility issues and can worsen symptoms of PCOS.
research 832 Variability in secretion of growth factors by platelets is intrinsic to alopecia patients undergoing platelet-rich plasma therapy
Hair growth treatment results vary because each patient's platelets release different levels of growth factors.
research Relation between dermal papilla cells and androgenetic alopecia
Dermal papilla cells play a key role in hair loss by responding to androgens.
research Terbinafine levels in serum, stratum corneum, dermis-epidermis (without stratum corneum), hair, sebum and eccrine sweat.
Terbinafine quickly builds up in skin and hair, staying effective for over 3 weeks.
research Differential expression of keratin and keratin associated proteins are linked with hair loss condition in spontaneously mutated inbred mice
Abnormal gene expression related to keratin causes hair loss in certain mice.
research Perifollicular Fibrosis: Pathogenetic Role in Androgenetic Alopecia
Androgen hormones cause hair follicle scarring in hair loss, and finasteride helps reduce it.
research Clinical relevance of testosterone and dihydrotestosterone metabolism in women
Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.
research Chapter 23. Therapeutic Control of Androgen Action
Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.
research Hirsutism and Virilization in the Female
The chapter explains the causes of excessive hair growth and masculinization in women and how to measure hormone levels related to these conditions.
research Steroid Hormones of Reproduction and Sexual Development
Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.
research Severe Insulin Resistance in a Pediatric Patient: Key Areas to Address in the Screening
The case emphasizes the need for careful screening in children for insulin resistance and related conditions.
research Premature Adrenarche
Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.
research Is dehydroepiandrosterone a hormone?
Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.
research What does the concept of the stem cell niche really mean today?
Stem cell niches support, regulate, and coordinate stem cell functions.
research An Update of Congenital Adrenal Hyperplasia
Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.