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research Estrogenic Potential of 2-Alkyl-4-(thio)chromenone 6-O-Sulfamates: Potent Inhibitors of Human Steroid Sulfatase

37 citations , September 2003 in “Journal of Medicinal Chemistry”

A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.

Transient Stimulation of TRPMLs Enhances the Functionality of HDPCs and Facilitates Hair Growth in Mice

research Transient stimulation of TRPMLs enhance the functionality of hDPCs and facilitate hair growth in mice

April 2024 in “Cellular signalling”

Activating TRPMLs helps human cells important for hair growth and increases hair growth in mice.

Proton Affinitive Derivatization for Highly Sensitive Determination of Testosterone and Dihydrotestosterone in Saliva Samples by LC-ESI-MS/MS

research Proton Affinitive Derivatization for Highly Sensitive Determination of Testosterone and Dihydrotestosterone in Saliva Samples by LC-ESI-MS/MS

8 citations , July 2018 in “Analytical sciences”

Using 5-butylpicolinate esters improves the sensitivity and reliability of detecting testosterone and dihydrotestosterone in saliva.

research Lipin 1 Gene Polymorphisms in Polycystic Ovary Syndrome

7 citations , March 2011 in “Hormone and Metabolic Research”

Certain gene variations might help protect against insulin resistance and glucose intolerance in people with Polycystic Ovary Syndrome.

research Phase 2, double-blind, randomized, placebo-controlled study of the safety and efficacy of elagolix in women with polycystic ovary syndrome

2 citations , February 2023 in “F&S Reports”

Elagolix did not effectively treat polycystic ovary syndrome.

research Hidradenitis suppurativa secondary to treatment with a gamma secretase inhibitor

1 citations , October 2023 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

A man developed skin lesions as a side effect of a gamma secretase inhibitor used for treating a tumor.

research Real-world single-center experience with 10 cases of generalized pustular psoriasis successfully treated with ixekizumab

21 citations , September 2019 in “Journal of the American Academy of Dermatology”

Ixekizumab effectively treats generalized pustular psoriasis.

research The effect of platelet-derived growth factor-aa (PDGFA) conjugated with low-molecular-weight protamine (LMWP) on hair loss improvement effect

December 2024 in “Biochemical and Biophysical Research Communications”

LMWP-PDGFA shows promise for improving hair health and treating hair loss with fewer side effects.

Steroid Sulfatase Inhibitors: Role and Therapeutic Potential

research Steroid sulfatase inhibitors

1 citations , January 2003 in “Expert Opinion on Therapeutic Patents”

Steroid sulfatase inhibitors could potentially treat hormone-related disorders like certain cancers, hair loss, acne, and improve cognitive dysfunction.

research A Functional Role of S100A4/Non-Muscle Myosin IIA Axis for Pro-Tumorigenic Vascular Functions in Glioblastoma

December 2021 in “Research Square (Research Square)”

S100A4 and NMIIA promote tumor growth in glioblastoma by enhancing blood vessel functions.

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