36 citations
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January 2010 in “Human & experimental toxicology” Eating paradise nuts led to selenium poisoning, causing nausea, hair loss, and other symptoms in two women.
30 citations
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January 2023 in “EFSA journal” Adults should not consume more than 255 micrograms of selenium per day to avoid risk of hair loss and other side effects.
16 citations
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May 2019 in “Hormone and Metabolic Research” Selenium might help with insulin resistance and cholesterol in PCOS, but more research is needed to confirm its benefits.
7 citations
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August 2025 in “Plants” Selenium from plants is beneficial and safer for health.
Selenium can be toxic to animals, causing serious health issues, especially in horses.
February 2019 in “Americanae (AECID Library)” Selenium and zinc deficiency in sheep leads to thyroid and skin problems.
618 citations
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January 2018 in “Cochrane Database of Systematic Reviews” Selenium supplements do not prevent cancer and may increase certain health risks.
382 citations
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February 2010 in “Archives of Internal Medicine” A manufacturing error in a dietary supplement caused severe selenium poisoning, affecting many people and highlighting the need for stricter quality control.
241 citations
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January 2001 in “Reviews on Environmental Health” High selenium exposure can harm thyroid function, immune system, liver, skin, and may increase neurotoxicity and cancer risk.
126 citations
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November 1987 in “The Journal of Pediatrics” Selenium deficiency can cause skin and hair color loss, muscle weakness, and blood cell changes, but these improve with selenium supplements.
115 citations
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December 1996 in “PubMed” The safe daily selenium intake is up to 819 micrograms.
93 citations
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March 2014 in “Cochrane Database of Systematic Reviews” Selenium supplements do not prevent cancer and may have harmful effects.
79 citations
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April 1996 in “JAMA” Taking too many selenium supplements can cause serious health problems like hair loss and fatigue.
78 citations
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December 2011 in “Clinical toxicology” Excessive selenium from a supplement caused toxicity but patients recovered with care.
71 citations
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June 2008 in “Annals of Internal Medicine” Excessive selenium from supplements can be harmful.
61 citations
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May 2010 in “Integrative Cancer Therapies” There is no clear recommendation for using selenium in cancer patients; it may be beneficial to correct low selenium levels before treatment.
55 citations
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February 1990 in “Journal of Nutrition” Selenium in hair and nails is higher with L-selenomethionine and low methionine.
49 citations
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February 2020 in “Scientific reports” The nanohybrid system significantly improved wound healing and showed strong antibacterial activity.
35 citations
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January 2001 in “Journal of Animal Science” High dietary selenium, especially inorganic, causes weight loss and selenosis in pigs, with effects varying by hair color.
35 citations
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April 1956 in “Journal of the American Medical Association” Selenium sulfide shampoo can cause hair loss, which stops when you stop using it.
30 citations
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September 2016 in “Aging Cell” Low selenium levels can extend lifespan but worsen health issues.
27 citations
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June 2010 in “Journal of the American Academy of Dermatology” Excessive selenium in supplements can cause hair loss and nail issues.
23 citations
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October 1995 in “PubMed” Selenium exposure at work caused the worker's complete hair loss.
23 citations
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August 1989 in “American Journal of Veterinary Research” High selenium diets in pigs cause health issues like weight loss, hair loss, and nerve damage.
22 citations
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August 2019 in “Environmental research” Pseudomonas sp. T5-6-I bacteria increase selenium uptake in Brassica oleracea plants by 130%.
21 citations
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June 1991 in “Journal of Inherited Metabolic Disease” Selenium deficiency caused symptoms in a child, which improved with selenium supplements.
20 citations
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February 2013 in “Nutrition” Selenium-enriched green tea might be a safe prebiotic for gut health.
20 citations
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August 1960 in “PubMed” Selenium sulfide may affect hair root health.
18 citations
,
September 2011 in “Livestock science” Maternal Nano-Se supplements improve fetal hair follicle development in cashmere goats.
16 citations
,
December 2005 in “Journal of Animal Physiology and Animal Nutrition” Moderate selenium levels in a dog's diet are best for hair growth.