174 citations
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November 2016 in “Cell stem cell” Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.
144 citations
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September 2012 in “Genes & development” Aging causes skin stem cells to work less effectively.
99 citations
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August 2009 in “Nature Genetics” Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.
68 citations
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December 2011 in “Journal of Investigative Dermatology” Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.
64 citations
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January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Human stem cells can help form hair follicles in mice.
36 citations
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September 2013 in “PLoS ONE” Sweat gland stem cells help maintain glands, aid wound healing, and can regenerate skin structures.
24 citations
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August 2022 in “Immunity” Type 2 immunity helps control mite growth in hair follicles, preventing damage.
20 citations
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October 2017 in “Stem Cell Reports” Alkaline Ceramidase 1 prevents early hair loss in mice by keeping hair follicle stem cells balanced.
3 citations
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May 2022 in “Oncogene” Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.
3 citations
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February 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.
1 citations
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May 2025 in “BMC Genomics” lncRNAs may help control cashmere goat hair growth by responding to light changes.
1 citations
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October 2012 in “Elsevier eBooks” Skin stem cells can help improve skin repair and regeneration.
May 2015 in “Journal of Investigative Dermatology” Wnt-3a helps grow more skin stem cells, which could lead to new hair loss treatments.
44 citations
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July 2016 in “Stem Cells Translational Medicine” Scientists discovered that certain stem cells from mice and humans can be used to grow new hair follicles and skin glands when treated with a special mixture.
July 2025 in “Biotechnology and Bioprocess Engineering” Camellia japonica seed extract helps hair grow by activating hair follicles and preventing cell aging.
20 citations
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February 2023 in “Biology” Innovative cosmetics could safely change hair color by targeting biological hair pigmentation processes.
18 citations
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October 2017 in “PLOS ONE” The study concluded that similar pathways regulate hair growth in dogs and mice, and these pathways are disrupted in dogs with Alopecia X, affecting stem cells and hormone metabolism.
August 2025 in “Frontiers in Pharmacology” Periplaneta americana extract helps hair regrowth by reducing inflammation and improving skin bacteria balance.
25 citations
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October 2012 in “Dermatologic clinics” Laser and light treatments can effectively remove hair long-term.
25 citations
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February 2024 in “Biomaterials” Stem cell-derived organoids can improve skin healing.
8 citations
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February 2022 in “Scientific Reports” Medicinal herbs might treat hair loss by affecting genes and pathways related to lipid and glycerophospholipid metabolism.
April 2025 in “Journal of Investigative Dermatology” Fibronectin is essential for hair follicle regeneration by supporting stem cells.
June 2023 in “Frontiers in Medicine” Protein tyrosine kinases are key in male pattern baldness, affecting skin structure, hair growth, and immune responses.
April 2022 in “Journal of Investigative Dermatology” Hair shaft miniaturization leads to hair follicle stem cell loss, suggesting Piezo1 as a potential treatment target.
503 citations
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May 2009 in “Cell stem cell” Lrig1 marks a unique group of stem cells in mouse skin that can become different skin cell types.
169 citations
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February 2018 in “Immunity” Inactive stem cells in hair follicles and muscles can avoid detection by the immune system.
33 citations
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March 2018 in “Trends in cell biology” Metabolism plays a key role in determining stem cell fate.
13 citations
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November 2022 in “Chemical Science” Inorganic-based biomaterials can quickly stop bleeding and help wounds heal, but they may cause issues like sharp ion release and pH changes.
6 citations
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July 2019 in “Experimental Dermatology” Skin can produce blood cells, often due to disease, which might lead to new treatments for skin and blood conditions.
136 citations
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September 2019 in “Journal of Clinical Investigation” Dermal adipose tissue in mice can change and revert to help with skin health.