March 2010 in “The Journal of Urology” Hair loss, prostate size, and urinary issues are related due to androgen effects.
Finasteride impairs sperm quality and fertility in rats, even after stopping treatment.
2 citations
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May 2012 in “Acta pharmaceutica sinica B” The study found unique microscopic features for hair or feather in five animal ingredients in Shenrongbian pill.
13 citations
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March 1999 in “Biochemical Journal” Overexpressing SSAT in mice makes them highly sensitive to polyamine analogues, causing liver damage and high mortality.
August 2011 in “Reproductive Toxicology” Finasteride affects prostate development differently in male and female Mongolian gerbils.
11 citations
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October 2005 in “Toxicological Sciences” Cigarette smoke condensates increase tumor-promoting markers in mouse skin, especially around hair follicles.
8 citations
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March 2012 in “Mass spectrometry letters” The S9 fraction with GC-IDMS is effective for measuring 5α-reductase activity.
5 citations
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October 2020 in “Journal of radiation research” Vesicles from irradiated mouse cheek skin help cells survive radiation.
1 citations
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October 2024 in “JCEM Case Reports” 5α-reductase deficiency can cause ambiguous genitalia and gender dysphoria, treatable with testosterone.