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5α-reductase affects dopamine receptors linked to sensorimotor gating, which may help understand disorders like schizophrenia.

Finasteride may help improve certain brain function issues linked to dopamine.

Neonatal neurosteroid levels affect adult brain function and behavior.

Blocking CYP17A1 enzyme may help improve certain brain function issues related to dopamine.

Finasteride worsens stress effects on sensory processes, possibly linking to anxiety/depression.

Finasteride reduces certain behaviors caused by D1-like receptor agonists but not by D2-like receptor agonists in mice.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Stress worsens Tourette symptoms by increasing allopregnanolone levels.

A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.

Isoallopregnanolone may be a safe and effective treatment for reducing tics in a mouse model of Tourette syndrome.

Allopregnanolone increases KCC2 expression in baby male rats' brains, while finasteride doesn't affect it.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

Finasteride reduces response to stress and rewards, affecting behavior and mental health.

Finasteride reduces movement issues in Parkinson's disease rats.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.

Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Dutasteride shows promise as a potential treatment for Parkinson's disease.

The document suggests creating a secure database for indigenous knowledge and recommends that the TKDL actively fight patents that slightly alter traditional knowledge.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.