March 2023 in “The Journal of Urology” Higher SRD5A2 expression predicts better response to finasteride in treating urinary symptoms.
January 2005 in “Dialnet (Universidad de la Rioja)” Post-SSRI sexual dysfunction syndrome was formally recognized in 2006, impacting clinical practice and research.
Blocking 5α-reductase can reduce sleep deprivation-related behavioral issues in rats.
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August 2017 in “International clinical psychopharmacology” Bupropion causes more hair loss than other antidepressants, with paroxetine causing the least.
Finasteride may cause depression and affect brain and gut health in male rats.
14 citations
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October 2016 in “Psychoneuroendocrinology” Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.
May 2022 in “Endocrine Abstracts” Finasteride may cause sexual dysfunction by reducing epinephrine levels.
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January 2025 in “International Journal of Molecular Sciences” Progesterone reduces anxiety and depression in female mice by increasing BDNF in the brain, needing 5α-reduction and estradiol.
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December 2008 in “Clinics in Dermatology” Escitalopram might effectively treat delusions of parasitosis and possibly Morgellons disease, with psychological factors being important to consider.
April 2021 in “Reactions Weekly” Finasteride increases risk of depression, possibly suicidal thoughts, and sexual dysfunction.
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July 2011 in “Journal of Neuroscience” Ethanol boosts brain steroid production by activating NMDA receptors, affecting memory formation.
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November 2021 in “British Journal of Clinical Pharmacology” Saw palmetto may cause erectile dysfunction and needs better safety monitoring.
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March 2019 in “Behavioural Brain Research” Finasteride use can cause depression-like behavior in male rats.
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October 2016 in “Iranian journal of psychiatry and behavioral sciences” Sertraline, an antidepressant, may rarely cause hair loss.
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January 2015 in “Case Reports in Urology” Venlafaxine can cause urinary incontinence in rare cases.
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August 2015 in “Neuropsychopharmacology” High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.
Finasteride may cause changes in dopamine-related genes, possibly leading to post-finasteride syndrome.
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June 2025 in “European Journal of Clinical Pharmacology” Finasteride may increase the risk of suicidality and depression, especially in younger people.
January 2020 in “Nihon Yakuri Gakkai nenkai yoshishu” Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.
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September 2017 in “Hormones and behavior” δ-GABAA receptors affect alcohol consumption based on the estrous cycle and influence movement regardless of the cycle.
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August 2021 in “Biomedicine & Pharmacotherapy” 5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.
January 2016 in “Medicinski Podmladak” Finasteride may increase anxiety in bright spaces.