July 2023 in “World Journal of Biology Pharmacy and Health Sciences” Trazodone and Chlorpromazine might help treat sexual dysfunction from finasteride and SSRIs.
February 2025 in “Iranian journal of pharmaceutical research” September 2022 in “Reactions Weekly” May 2025 in “Reactions Weekly”
3 citations
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January 2015 in “Case reports in psychiatry” Sertraline can cause hair loss, which stops after stopping the drug.
12 citations
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April 2018 in “Physiology & Behavior” Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.
25 citations
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June 2017 in “Neuropharmacology” Increasing TSPO in the brain reduces anxiety and depression.
November 2023 in “Frontiers in Neuroendocrinology” Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.
May 2024 in “Reactions weekly” May 2011 in “Psychiatric News” Horizant has risks like other seizure drugs, Johnson & Johnson misled about Risperdal, and Quanterix found a possible link between brain oxygen loss and Alzheimer's markers.
August 2025 in “medRxiv (Cold Spring Harbor Laboratory)” 5-alpha reductase inhibitors may increase depression risk by 31%, but results vary based on comparison groups.
July 2007 in “Journal of Generic Medicines” The UK High Court revoked Lundbeck's patent for Escitalopram, and second medical use claims based on dosage were not considered novel.
October 2025 in “Reactions Weekly” March 2023 in “Brazilian Journal of Health Review” The combination tablet of finasteride and doxazosin works the same as taking each drug separately.
1 citations
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June 2025 in “European Journal of Clinical Pharmacology” Finasteride may increase the risk of suicidality and depression, especially in younger people.
7 citations
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October 2017 in “Behavioural Pharmacology” Fluoxetine's effectiveness as an antidepressant in mice depends on a specific protein activity and a 5-minute pretest.
September 2004 in “Inpharma Weekly”
12 citations
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August 2018 in “Psychiatry research” Estazolam reduces anxiety-like behavior in PTSD by increasing allopregnanolone levels.
December 2006 in “The Brown University Psychopharmacology Update” Second-generation antipsychotics offer no significant benefit over first-generation ones for schizophrenia.
May 2024 in “News Digital Object Group” May 2024 in “Reactions weekly”
90 citations
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March 2017 in “JAMA Internal Medicine” Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.
72 citations
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January 2011 in “Current Pharmaceutical Design” S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.
2 citations
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October 2002 in “American Journal of Nursing” Taking the same medication under different brand names caused harmful side effects.
January 2011 in “Reactions Weekly” 19 citations
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July 2023 in “Neuroscience & Biobehavioral Reviews” Endogenous neurosteroids may set a baseline mood.
54 citations
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May 2018 in “International journal of risk & safety in medicine” Antidepressants, 5α-reductase inhibitors, and isotretinoin can cause long-lasting sexual dysfunction.
May 2024 in “Reactions weekly”
May 2025 in “Psychopharmacology” Chronic finasteride use in male rats doesn't strongly cause depression or anxiety due to adaptive stress hormone changes.
April 2016 in “Journal of The American Academy of Dermatology” Finasteride and SSRIs together increase impotence and low libido risk in men.