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GlossarySerum Levels

amount of a substance in the blood's liquid component

Serum levels, also known as blood serum levels or serum concentration, refer to the amount of a specific substance present in the liquid part of the blood after the blood has clotted and the cells have been removed. These measurements are crucial for diagnosing and monitoring various medical conditions, as they can indicate the presence and severity of diseases, the effectiveness of treatments, or the body's response to medications.

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Serum Dihydrotestosterone Levels Are Associated With Adverse Myocardial Remodeling in Patients With Severe Aortic Valve Stenosis Before and After Aortic Valve Replacement

research Serum dihydrotestosterone levels are associated with adverse myocardial remodeling in patients with severe aortic valve stenosis before and after aortic valve replacement

4 citations , October 2022 in “American journal of physiology. Heart and circulatory physiology”

Higher DHT levels are linked to worse heart changes in severe aortic valve stenosis patients.

Associations Between Serum Dihydrotestosterone Levels, Lipid Parameters, and Anthropometric Measurements in Male Patients with Type 2 Diabetes Mellitus

research associations between serum dihydrotestosterone levels, lipid parameters & anthropometric measurements in male patients with type 2 diabetes mellitus

July 2022 in “International Journal of Health Sciences (IJHS) (En línea)”

Men with Type 2 Diabetes have lower DHT levels, which may affect fertility and lipid profiles.

research The effects of finasteride on scalp skin and serum androgen levels in men with androgenetic alopecia

65 citations , October 1999 in “Journal of The American Academy of Dermatology”

Finasteride effectively reduces hair loss by decreasing androgen levels.

research Sex steroid levels in corresponding cerebrospinal fluid and serum samples quantified by mass spectrometry in men

1 citations , November 2023 in “Endocrine Connections”

DHEA is the main sex steroid in cerebrospinal fluid, and testosterone in the fluid comes from the blood.

Serum Androgens and Prostate-Specific Antigen Levels in Androgenetic Alopecia: Is There a Difference Between Frontal and Vertex Baldness?

research Serum androgens and prostate-specific antigen levels in androgenetic alopecia: is there a difference between frontal and vertex baldness?

1 citations , December 2017 in “Journal of The European Academy of Dermatology and Venereology”

Vertex baldness has higher DHT levels than frontal baldness, but testosterone and PSA levels are similar.

research BENIGN PREMATURE ADRENARCHE: CLINICAL FEATURES AND SERUM STEROID LEVELS

77 citations , September 1983 in “Acta Paediatrica”

Dexamethasone effectively normalizes elevated steroid levels in girls with premature adrenarche.

S1 Opioid Receptor Agonists and Serum Prostate-Specific Antigen Level: Is There a Role for Prostate Cancer Control and Chemoprevention?

research S1 OPIOID RECEPTOR AGONISTS AND SERUM PROSTATE SPECIFIC ANTIGENE LEVEL: IS THERE A ROLE FOR PROSTATE CANCER CONTROL AND CHEMOPREVENTION?

September 2010 in “European Urology Supplements”

Opioid use may lower PSA levels, suggesting a possible role in prostate cancer control; PSA testing is useful for detecting prostate cancer; serum triglycerides are not linked to prostate cancer risk; and higher urethral PSA levels may be associated with local hormone activity.

research Serum Levels of Androgen-Associated Hormones Are Correlated with Curative Effect in Androgenic Alopecia in Young Men

9 citations , October 2018 in “Medical Science Monitor”

Lowering certain hormone levels improves treatment for hair loss in young men.

research Correlations of the onset of androgenic alopecia with family history and serum dihydrotestosterone levels in 614 female patients

December 2024 in “Chinese Journal of Dermatology”

Higher DHT levels and family history lead to earlier hair loss in women.

research Role of serum androgens and prostate-specific antigen levels in males with androgenetic alopecia

September 2019 in “Human Andrology”

Higher serum androgens contribute to male pattern baldness.

Preponderance of Serum and Intra-Hepatic 5α-Dihydrotestosterone in Males with Hepatocellular Carcinoma Despite Low Circulating Androgen Levels

research Preponderance of serum and intra-hepatic 5α-dihydrotestosterone in males with hepatocellular carcinoma despite low circulating androgen levels

8 citations , January 1986 in “Journal of hepatology”

Men with liver cancer have higher levels of a specific testosterone byproduct in their liver and blood, despite overall lower male hormone levels.

research Role of serum androgens and prostate-specific antigen levels in men with androgenetic alopecia

1 citations , January 2020 in “Egyptian Journal of Dermatology and Venereology”

Higher testosterone and DHT levels are linked to hair loss in men, but not to prostate cancer risk.

research Changes of sex hormone levels in male acne patients with normal serum testosterone and effect of antiandrogen therapy

January 2009 in “Academic Journal of Second Military Medical University”

Finasteride with lifestyle changes effectively treats acne in males by improving hormone levels and reducing recurrence.

Effects of the 5α-Reductase Inhibitor Finasteride on Serum Levels of Gonadal, Adrenal, and Hypophyseal Hormones and Its Clinical Significance: A Prospective Clinical Study

research Effects of the 5α-Reductase Inhibitor Finasteride on Serum Levels of Gonadal, Adrenal, and Hypophyseal Hormones and its Clinical Significance: A Prospective Clinical Study

56 citations , April 1998 in “Steroids”

Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.

research Comparative Efficacy of Oral and Topical 5-Alpha Reductase Inhibitors in Reducing Dihydrotestosterone levels across Men with Androgenetic Alopecia: A Network Meta-Analysis incorporating Post-Hoc Analyses of Randomized Clinical Trial Data

January 2026 in “Open Science Framework”

Oral and topical 5-alpha reductase inhibitors affect DHT levels and hair density differently in treating hair loss.

The Effect of 5α-Reductase Inhibition With Dutasteride and Finasteride on Bone Mineral Density, Serum Lipoproteins, Hemoglobin, Prostate Specific Antigen, and Sexual Function in Healthy Young Men

research The Effect of 5α-Reductase Inhibition With Dutasteride and Finasteride on Bone Mineral Density, Serum Lipoproteins, Hemoglobin, Prostate Specific Antigen and Sexual Function in Healthy Young Men

72 citations , April 2008 in “The Journal of urology/The journal of urology”

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

Relations Between Sex Hormone Levels and Characteristics of Hair and Skin in Healthy Young Men

research Relations between sex hormone level and characters of hair and skin in healthy young men

18 citations , May 1992 in “American Journal of Biological Anthropology”

Higher androgen levels do not cause baldness in men.

research S4 URETHRAL PSA LEVELS AFTER RADICAL PROSTATECTOMY

September 2010 in “European Urology Supplements”

Higher urethral PSA levels after prostate removal surgery may be linked to more hair loss and higher PSA levels post-surgery.

research Topical MK-386 (M), an inhibitor of 5α-reductase (5αr) type I, suppresses sebum dht.

February 1996 in “Clinical Pharmacology & Therapeutics”

MK-386 reduces sebum DHT levels.

research The Serum Evaluation of Sex Hormones Including DHEAs, DHT, Testosterone in Oral Lichen Planus Patients

April 2025

Oral lichen planus is not linked to sex hormone levels.

research Serum concentrations of dihydrotestosterone are associated with symptoms of hypogonadism in biochemically eugonadal men

5 citations , April 2021 in “Journal of Endocrinological Investigation”

Higher DHT levels are linked to fewer hypogonadism symptoms in men with normal testosterone levels.

research DUTASTERIDE AS AN EFFECTIVE TREATMENT IN ANDROGENETIC ALOPECIA – A LITERATURE REVIEW

September 2025 in “International Journal of Innovative Technologies in Social Science”

Dutasteride is more effective than finasteride for hair loss, but more research is needed on safety and dosing.

Oral and Topical Administration of Standardized Saw Palmetto Oil Reduces Hair Fall and Improves Hair Growth in Androgenetic Alopecia Subjects: A 16-Week Randomized, Placebo-Controlled Study

research Oral and Topical Administration of a Standardized Saw Palmetto Oil Reduces Hair Fall and Improves the Hair Growth in Androgenetic Alopecia Subjects – A 16-Week Randomized, Placebo-Controlled Study

November 2023 in “Clinical, Cosmetic and Investigational Dermatology”

Saw palmetto extract reduced hair loss and improved hair growth in people with hair thinning.

research Assessment of the usefulness of dihydrotestosterone in the diagnostics of patients with androgenetic alopecia

35 citations , January 2014 in “Postepy Dermatologii I Alergologii”

DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.

Efficacy and Safety of Topical Combination of 3% Minoxidil and 0.25% Finasteride Versus 3% Minoxidil Solution in Female-Pattern Hair Loss: A Randomized, Double-Blind, Controlled Study

research Efficacy and safety of topical combination of 3% minoxidil and 0.25% finasteride versus 3% minoxidil solution in female-pattern hair loss: A randomized, double-blind, controlled study

1 citations , August 2018 in “Journal of The American Academy of Dermatology”

Combination of minoxidil and finasteride is more effective in increasing hair diameter than minoxidil alone for female-pattern hair loss.

Oral Testosterone in Oil: Pharmacokinetic Effects of 5α-Reduction by Finasteride or Dutasteride and Food Intake in Men

research Oral Testosterone in Oil: Pharmacokinetic Effects of 5 Reduction by Finasteride or Dutasteride and Food Intake in Men

22 citations , January 2006 in “International Journal of Andrology”

Taking oral testosterone with finasteride or dutasteride doubles testosterone levels, and food slightly affects it.

Androgenetic Alopecia: Hair Loss Effectively Stopped with 1 mg Finasteride

research [Androgenetic alopecia. Hair loss effectively stopped with 1 mg Finasterid].

May 1999 in “PubMed”

Taking 1 mg of finasteride can effectively stop hair loss.

Inhibitory Activities of Some Traditional Chinese Herbs Against Testosterone 5α-Reductase and Effects of Cacumen Platycladi on Hair Regrowth in Testosterone-Treated Mice

research Inhibitory activities of some traditional Chinese herbs against testosterone 5α-reductase and effects of Cacumen platycladi on hair re-growth in testosterone-treated mice

25 citations , November 2015 in “Journal of Ethnopharmacology”

Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.

research The Effect of Leonuri Herba alkaloids on Senile BPH (male and female hormone induced) model rats

4 citations , March 2017 in “Al-Mi’galaẗ al-sa'udiyaẗ lī-ulum al-ḥayaẗ”

Leonuri Herba alkaloids may help treat hormone-induced enlarged prostate in rats.

research The role of androgens in hormone replacement therapy

6 citations , September 2005 in “Expert Opinion on Pharmacotherapy”

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.