research Reversal of androgenetic alopecia by topical ketoconzole: Relevance of anti-androgenic activity
Ketoconazole lotion can improve hair regrowth for some people with androgenetic alopecia.
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research The Mesenchymal Niche of the Hair Follicle Induces Regeneration by Releasing Primed Progenitors from Inhibitory Effects of Quiescent Stem Cells
The study found that a specific area of the hair follicle helps start hair growth by reducing the blocking effects on certain cells and controlling growth signals.
research Tacrolimus in Dermatology
Tacrolimus is effective for various skin conditions with fewer side effects than cyclosporine.
research Biphasic Effects of Minoxidil on the Proliferation and Differentiation of Normal Human Keratinocytes
Minoxidil affects cell growth in two ways: low doses increase growth, while high doses slow it down and can be toxic.
research Evaluation of Oral Minoxidil in the Treatment of Alopecia Areata
Oral minoxidil helps hair regrowth in 80% of alopecia patients, but only 18% see cosmetic improvement.
research Androgenic Hormone Profile of Adult Women with Acne
Over half of the adult women with acne in the study had higher than normal levels of male hormones, especially DHEA.
research Dutasteride reduces alcohol’s sedative effects in men in a human laboratory setting and reduces drinking in the natural environment
Dutasteride makes alcohol less sedating and may lead to less drinking in men.
research Blimp1+ cells generate functional mouse sebaceous gland organoids in vitro
Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.
research Unchanged androgen-binding properties of sex hormone-binding globulin in male patients with liver cirrhosis
SHBG binding properties are unchanged in male liver cirrhosis patients.
research Hirsutism: diagnosis and treatment
The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.
research Pregnancy and Skin
Most skin changes during pregnancy are harmless and temporary, but some can risk the fetus and need careful treatment.
research Apoptotic cells represent a dynamic stem cell niche governing proliferation and tissue regeneration
Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.
research Androgen receptor in rat liver: Characterization and separation from a male-specific estrogen-binding protein
Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.
research Thyroid antibodies in Hashimoto’s thyroiditis patients are positively associated with inflammation and multiple symptoms
Higher thyroid antibodies in Hashimoto's thyroiditis are linked to more inflammation and symptoms.
research 5α-Reductase isozymes and aromatase mRNA levels in plucked hair from young women with female pattern hair loss
Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.
research Pharmacologic Treatment of Polycystic Ovary Syndrome
The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.
research Apocrine sweat gland obstruction by antiperspirants allowing transdermal absorption of cutaneous generated hormones and pheromones as a link to the observed incidence rates of breast and prostate cancer in the 20th century
The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.
research The Phytocannabinoid (–)-Cannabidiol Operates as a Complex, Differential Modulator of Human Hair Growth: Anti-Inflammatory Submicromolar versus Hair Growth Inhibitory Micromolar Effects
CBD can either reduce inflammation and not affect hair growth at low levels or inhibit hair growth at high levels.
research Stimulation of elastin expression by minoxidil in chick skin fibroblasts
Minoxidil boosts elastin production, potentially helping skin diseases.
research Clinical efficacy of oral administration of finasteride at a dose of 2.5 mg/day in women with female pattern hair loss
Finasteride 2.5 mg/day can effectively treat female hair loss.
research Induction of insulin‐like growth factor‐I by cepharanthine from dermal papilla cells: A novel potential pathway for hair growth stimulation
Cepharanthine may help hair growth by increasing IGF-I in scalp cells.
research Assessment of Vitamin D Level in Patients of Alopecia Areata
Low vitamin D levels are common in people with Alopecia Areata.
research The influence of CD26+ and CD26− fibroblasts on the regeneration of human dermo-epidermal skin substitutes
CD26+ fibroblasts improve skin healing and integration better than CD26− fibroblasts.
research Finasteride-Induced Inhibition of 5α-Reductase Type 2 Could Lead to Kidney Damage—Animal, Experimental Study
Finasteride may cause kidney damage.
research Management of Recurrent Ischemic Priapism 2014: A Complex Condition with Devastating Consequences
Effective, well-tolerated, and affordable treatments are needed for recurrent ischemic priapism.
research Association of vitamin D level with alopecia areata
Vitamin D levels are not linked to alopecia areata.
research THERAPEUTIC HOTLINE: Treatment of androgenic alopecia with finasteride may result in a high grade prostate cancer in patients: fact or fiction?
Finasteride for hair loss is safe and does not increase the risk of high-grade prostate cancer.
research Rapid full engraftment and successful immune reconstitution after allogeneic hematopoietic stem cell transplantation with reduced intensity conditioning in Omenn syndrome
A five-month-old boy with Omenn syndrome successfully recovered after a stem cell transplant with reduced intensity conditioning.
research Testosterone Treatment in Women – An Overview
Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.
research URB expression in human dermal papilla cells
The gene URB is more active in human hair growth cells and responds to a hair-related hormone.