December 2011 in “Korean journal of veterinary research” A Miniature Pinscher dog with hair loss and scaling was diagnosed with pattern alopecia and improved with melatonin treatment.
19 citations
,
January 2007 in “Biological & pharmaceutical bulletin” Glycine reduces skin pigmentation by lowering melanin production.
2 citations
,
January 2020 in “BioMed Research International” Phaeodactylum tricornutum extract helps hair follicle cells grow by activating the ERK1/2 pathway.
16 citations
,
January 2008 in “Acta dermato-venereologica” Vitamin B12 deficiency can cause skin darkening and increased blood vessels, but treatment can improve symptoms.
2 citations
,
June 2025 in “International Journal of Molecular Sciences” Chitosan and melatonin together improve wound healing and have potential in medicine and cosmetics.
May 2025 in “Veterinary Medicine and Science” Melatonin improved reproductive function in male Pomeranian dogs with Alopecia X, but more research is needed.
9 citations
,
July 2021 in “Frontiers in genetics” Melatonin makes cashmere grow earlier and more by increasing certain gene activity in goats.
8 citations
,
February 2005 in “Veterinary dermatology” Chesapeake Bay retrievers' hair loss is likely a breed-specific, hereditary condition linked to abnormal steroid levels and distinct skin changes.
11 citations
,
August 2018 in “Asian-Australasian journal of animal sciences” Short daily photoperiods improve cashmere production in Inner Mongolia white cashmere goats.
40 citations
,
May 2014 in “PLoS ONE” Chronic stress can reduce skin pigmentation.
2 citations
,
December 2023 in “Royal Society of Chemistry eBooks” Hair is a complex organ, and understanding its detailed structure and growth phases is crucial for analyzing substances within it.
April 2015 in “한국생물공학회 학술대회” Finasteride reduces melanin production in skin cells.
50 citations
,
February 2013 in “Annals of Clinical Biochemistry” Understanding how DHT works is important for diagnosing and treating hormone-related disorders.
1 citations
,
January 2021 in “Processes” Researchers successfully grew horse skin cells that produce pigment from hair follicle samples.
April 2020 in “Arquivo Brasileiro De Medicina Veterinaria E Zootecnia” A horse in Brazil had seasonal hair loss possibly linked to light exposure and melatonin levels.
October 2021 in “Cosmoderma” Hair loss can be managed with treatments like minoxidil, finasteride, and others, but there are still gaps in effectiveness and off-label usage is increasing.
15 citations
,
June 2021 in “International Journal of Molecular Sciences” CMC2.24 and CMC2.23 reduce melanin safely and effectively.
4 citations
,
February 2025 in “Pharmaceuticals” Voglibose may help treat skin hyperpigmentation safely.
November 2025 in “Frontiers in Veterinary Science” A 1.0% tyrosine diet increases melanin in chicken feathers.
5 citations
,
June 2020 in “Experimental dermatology” Redheaded people may have evolved to efficiently make vitamin D in areas with less sunlight.
January 2019 in “Figshare” Redheaded people have higher levels of vitamin D precursor, suggesting their hair color may be an adaptation to low sunlight areas.
41 citations
,
September 2014 in “Journal of Pharmacy and Pharmacology” Melatonin may help treat PCOS symptoms in rats.
8 citations
,
August 2020 in “Domestic Animal Endocrinology” Melatonin improved cashmere production in goats during the first cycle but had no lasting effects on the next cycle.
39 citations
,
January 2012 in “International Journal of Trichology” Melatonin solution helps treat hair loss in men and women.
7 citations
,
January 2016 in “Hair therapy & transplantation” People with early graying hair often have lower levels of iron, ferritin, and calcium.
1 citations
,
February 2022 in “Open Access Macedonian Journal of Medical Sciences” Low zinc levels might contribute to early hair graying.
47 citations
,
May 1999 in “Reproduction” Goat reproductive activity and coat growth are affected by light and temperature, with temperature altering prolactin levels and hair growth, but not melatonin or estrus onset.
63 citations
,
March 2016 in “International Journal of Molecular Sciences” Children with atopic dermatitis often have sleep problems due to itching and may benefit from melatonin, which helps with sleep and skin symptoms.
17 citations
,
January 2006 in “Veterinary Dermatology” Topical melatonin and brushing did not affect hair regrowth in Siberian Huskies.
17 citations
,
June 2021 in “Molecules” Melatonin-loaded nanocarriers improve melatonin delivery and effectiveness for various medical treatments.