research Dermatologic Conditions in Transgender Populations
Transgender patients need proper skin care, especially when undergoing hormone treatments, to manage issues like acne and hair loss.
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research Androgenetic Alopecia: Overview
AGA is a genetic, hormonal hair loss treated with finasteride, minoxidil, and supplements, but new compounds are being developed.
research Insulin resistance, nitric oxide, and fibrinogen levels in white hirsute women: Defining a new paradigm based on translational research
White hirsute women with PCOS have higher insulin resistance, but similar nitric oxide and fibrinogen levels compared to those with idiopathic hirsutism.
research Impact of ustekinumab on quality of life and sexual difficulties associated with psoriasis: Results from phase III clinical trials
Ustekinumab significantly improved sexual function and quality of life for people with moderate to severe psoriasis.
research Urinary symptoms in patients with androgenetic alopecia
Lower nitric oxide and higher fibrinogen found in hirsute women; impaired sexual function in 22.6% of hair loss patients, linked to psoriasis severity.
research Finasteride-Induced Inhibition of 5α-Reductase Type 2 Could Lead to Kidney Damage—Animal, Experimental Study
Finasteride may cause kidney damage.
research Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARα and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways
Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.
research Research advances of tissue-derived extracellular vesicles in cancers
Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.
research Steroid Hormones
Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.
research 5α-reductase inhibitors
5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.
research Effect of ethanol extract of plant mixture on hair regeneration in human dermal papilla cells and C57BL/6J mice
A plant mixture extract helped grow hair by boosting cell growth and growth factors while blocking a hair loss-related enzyme.
research Effect of Testosterone Supplementation With and Without a Dual 5α-Reductase Inhibitor on Fat-Free Mass in Men With Suppressed Testosterone Production
Testosterone's muscle-building effects do not require its conversion to DHT.
research A Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Effectiveness of Botanically Derived Inhibitors of 5-α-Reductase in the Treatment of Androgenetic Alopecia
Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.
research A Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Effectiveness of Botanically Derived Inhibitors of 5-α-Reductase in the Treatment of Androgenetic Alopecia
Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.
research Morphometric-stereological and functional epididymal alterations and a decrease in fertility in rats treated with finasteride and after a 30-day post-treatment recovery period
Finasteride causes lasting fertility decrease in rats.
research A Perspective on the Evolving Landscape in Male Reproductive Medicine
Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.
research Nonsurgical Therapy for Hair Loss
Some nonsurgical hair loss treatments are effective, especially if started early.
research A concise review- Development of an analytical method and validation of dutasteride
New methods for measuring dutasteride are effective and reliable.
research New Drugs: Eculizumab
Eculizumab helps reduce blood transfusions and stabilize hemoglobin but increases infection risk and is expensive.
research A Case-Control Study of Physical Activity, Obesity and Energy intake and the Risk of Kidney Cancer
Being obese and eating too many calories may increase the risk of kidney cancer, but physical activity doesn't seem to affect this risk.
research Colon Cancer Stem Cells: Promise of Targeted Therapy
Targeting colon cancer stem cells might lead to better treatment results.
research Prostaglandin D 2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia
PGD2 stops hair growth and is higher in bald men with AGA.
research No evidence for the immunocompetence handicap hypothesis in male humans
Higher free testosterone levels in men are linked to a stronger immune response, not weaker.
research Critical Analysis on Characterization, Systemic Effect, and Therapeutic Potential of Beta-Sitosterol: A Plant-Derived Orphan Phytosterol
Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.
research Finasteride in the treatment of alopecia
Finasteride effectively treats male pattern baldness, improving hair growth and density.
research Human genetic basis of coronavirus disease 2019
Genetic differences affect COVID-19 severity and treatment development.
research New approaches to the treatment of osteoporosis
Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.
research Dihydrotestosterone-induced hair regrowth inhibition by activating androgen receptor in C57BL6 mice simulates androgenetic alopecia
DHT stops hair regrowth in mice, similar to human hair loss.
research Antibody-Capped Mesoporous Nanoscopic Materials: Design of a Probe for the Selective Chromo-Fluorogenic Detection of Finasteride
Probe detects finasteride with high selectivity and low detection limit.
research Progesterone-induced stimulation of mammary tumorigenesis is due to the progesterone metabolite, 5α-dihydroprogesterone (5αP) and can be suppressed by the 5α-reductase inhibitor, finasteride
Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.