research Sleep Problems are Associated with Development and Progression of Lower Urinary Tract Symptoms: Results from REDUCE
Poor sleep is linked to a higher risk of developing and worsening urinary problems in men.
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research Multiple readout assay for hormonal (androgenic and antiandrogenic) and cytotoxic activity of plant and fungal extracts based on differential prostate cancer cell line behavior
The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.
research The endocrinology of baldness
Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.
research The role of diet in the management of psoriasis: a scoping review
Higher fiber intake may reduce psoriasis severity, but more research is needed for effective dietary strategies.
research Apocrine sweat gland obstruction by antiperspirants allowing transdermal absorption of cutaneous generated hormones and pheromones as a link to the observed incidence rates of breast and prostate cancer in the 20th century
The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.
research The probable destructive mechanisms behind COVID-19 on male reproduction system and fertility
COVID-19 may harm male fertility and damage the reproductive system.
research Persistent Erectile Dysfunction after Discontinuation of 5-Alpha Reductase Inhibitor Therapy in Rats Depending on the Duration of Treatment
Long-term use of dutasteride can cause permanent erectile dysfunction in rats.
research Evaluation and Treatment of Gender Dysphoria to Prepare for Gender Confirmation Surgery
The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.
research Treatments options for alopecia
The document concludes that oral finasteride and topical minoxidil are effective for genetic hair loss, while other treatments for different types of hair loss show promise but need more research.
research Recent discoveries and developments of androgen receptor based therapy for prostate cancer
New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.
research Safety aspects of androgen treatment with 5α-dihydrotestosterone
DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.
research Identification of key genes induced by platelet-rich plasma in human dermal papilla cells using bioinformatics methods
Platelet-rich plasma may help hair follicle cells grow by affecting certain genes and pathways.
research The promise and challenges of cell therapy for psoriasis*
Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.
research Protective effects of finasteride against testosterone-induced calcium oxalate crystallization and crystal-cell adhesion
Finasteride helps prevent kidney stones, but side effects need more research.
research Macrophages maintain mammary stem cell activity and mammary homeostasis via TNF-α-PI3K-Cdk1/Cyclin B1 axis
Macrophages help maintain mammary stem cells and tissue balance through specific signaling pathways.
research Finasteride for prostatic disease: an updated and comprehensive review
Finasteride helps treat prostate issues and may prevent prostate cancer in high-risk men.
research Antiandrogen therapy for androgenetic alopecia
Antiandrogen therapy helps treat genetic hair loss.
research Resident CD34-positive cells contribute to peri-endothelial cells and vascular morphogenesis in salivary gland after irradiation
CD34-positive cells help repair and form new blood vessels in salivary glands after radiation.
research Androgen Receptor in Human Health: A Potential Therapeutic Target
The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.
research Inhibitory Effects of Serenoa repens on the Kinetic of Pig Prostatic Microsomal 5α-Reductase Activity
Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.
research Development of growth factor-incorporating liposomes for integration into scaffolds as a method to improve tissue regeneration
Liposomal carriers can improve tissue regeneration by stabilizing and retaining growth factors.
research Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases
New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
research Impact of Alpha Blockers, 5-alpha Reductase Inhibitors and Combination Therapy on Sexual Function
Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.
research The Long-Term Effect Of Specific Type II 5α-Reductase Inhibition With Finasteride on Bone Mineral Density in Men: Results of a 4-Year Placebo Controlled Trial
Finasteride doesn't harm bone density in older men with BPH.
research LncRNA-XIST promotes dermal papilla induced hair follicle regeneration by targeting miR-424 to activate hedgehog signaling
XIST RNA helps regenerate hair follicles by targeting miR-424 and activating hedgehog signaling.
research Treatment of Postsurgical Scalp Scar Deformity Using Follicular Unit Hair Transplantation
Hair transplantation effectively treats scalp scars with high success and patient satisfaction.
research Common Dermatologic Disorders in Down Syndrome: Systematic Review
People with Down syndrome often have skin issues and need regular check-ups for early treatment.
research Recommendations of endocrine treatment for patients with gender dysphoria
The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.
research Expression of E-SOD, GPX5 mRNAs and immunoexpression of Cu/ZnSOD in epididymal epithelial cells of finasteride-treated rats
Finasteride changes antioxidant enzyme expression, possibly affecting sperm protection in rats.
research Emerging lipid–polymer hybrid nanoparticles for genome editing
Lipid–polymer hybrid nanoparticles can improve genome editing delivery and outcomes.