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Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.

Mutations in the DSG4 gene cause fragile, sparse hair in humans, mice, and rats.

Blocking TGFβ-RI signaling enhances surface ectoderm differentiation from human stem cells.

Certain substances can decrease or increase exploratory behavior in rodents.

Deleting a specific protein in skin cells disrupts normal hair growth and development.

SPT6 prevents excessive skin inflammation by blocking a feedback loop.

The treatment was ineffective in humans.

A mutation in the HOXC13 gene causes hair and nail problems in a Syrian family.

Stat3 influences keratinocyte stem cell behavior, affecting differentiation and migration.

The mutation causing Hutchinson-Gilford progeria syndrome leads to severe skin problems and early death in mice.

A rare genetic mutation causes severe immune issues, hair loss, and nail problems.

Melanocyte-associated antigens may play a key role in alopecia areata and could be targets for new treatments.

Overexpressing noggin in mice causes severe osteoporosis.

The we/we wal/wal mice have defects in hair growth and skin layer formation, causing hair loss, useful for understanding alopecia.

The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.

Genetic mutations that disrupt homocysteine breakdown lead to increased damage in mouse hair keratin.

Disrupting the Hars2 gene in mice causes hearing loss due to mitochondrial problems and hair cell damage.

Mice with damaged skin or hair follicles are more susceptible to anthrax infection.

Overexpressing the glucocorticoid receptor in mice leads to abnormal skin development and reduced inflammation.

Dupilumab effectively treats severe skin issues in a rare genetic disorder.

The oncoprotein causes abnormal hair growth without increasing skin cancer risk.

Bleomycin injections in mice cause skin thickening and hair loss.

A gene called Taqpep affects cat coat patterns like stripes and blotches.

A protein called ectodysplasin-A2 increases a hair growth inhibitor in balding cells, which could be a target for hair loss treatment.

Blocking casein kinase 1 in skin cells can help melanocyte precursors move better, potentially helping with conditions like vitiligo or gray hair.

KLF4 is important for maintaining skin stem cells and helps heal wounds.

Sostdc1 controls the size and number of hair and mammary gland structures.

Wnt, Eda, and Shh pathways are crucial for different stages of sweat gland development in mice.

Genetically modified rats help reveal how vitamin D affects bone and skin health.