November 2013 in “Annales de Dermatologie et de Vénéréologie” Cinnamon essential oil can cause severe or unusual skin reactions, with cinnamaldehyde being the main allergen.
June 2023 in “Dermatology and Therapy” Using fractional CO2 laser with halometasone cream works better for chronic hand eczema than just the cream, improving symptoms and quality of life with fewer relapses.
36 citations
,
May 2005 in “BMC dermatology” DPCP is effective for treating severe alopecia areata, but relapse is common.
4 citations
,
January 2019 in “Einstein (São Paulo)” Dupilumab improved severe atopic dermatitis in a patient who didn't respond to other treatments.
November 2025 in “The Journal of Dermatology” Nemolizumab improved both severe atopic dermatitis and alopecia areata in one patient.
1 citations
,
May 2023 in “The Journal of Dermatology” Allergen-specific immunotherapy can significantly improve hair loss and dermatitis symptoms in severe cases.
1 citations
,
October 2020 in “Journal of The American Academy of Dermatology” Balding might help identify men at higher risk for severe COVID-19, but more research is needed.
11 citations
,
October 2011 in “Allergologia et immunopathologia” A girl with Netherton syndrome was able to eat wheat without allergies after a special treatment.
57 citations
,
March 2011 in “Pediatric Dermatology” Nearly half of children with primary immunodeficiency disorders showed skin problems, often as the first sign of their condition.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Bhringraj (Eclipta alba) is a significant herb known for its medicinal properties, particularly in treating liver and hair growth issues. It is effective in addressing premature graying, stopping hair loss, and promoting hair growth. Additionally, Bhringraj is beneficial for various skin conditions, including eczema, chronic wounds, skin ulcers, and severe itching. It also enhances liver function, reduces constipation, improves digestion, boosts metabolism, and stimulates bile production.
31 citations
,
July 2017 in “Journal of the American Academy of Dermatology” Apremilast improved symptoms in patients with severe skin conditions.
14 citations
,
January 2015 in “Skin Appendage Disorders” Brazilian keratin treatment can cause severe skin reactions.
September 2019 in “Journal of Investigative Dermatology” Abrocitinib at 100 mg and 200 mg daily may significantly improve moderate-to-severe atopic dermatitis in patients 12 years and older.
Dupilumab helped improve skin and prevent new lesions in a child with a rare immune disorder and severe eczema.
October 2022 in “Portuguese journal of dermatology and venereology” Dupilumab led to complete hair regrowth and improved skin condition in a young man with severe eczema and hair loss.
8 citations
,
September 2004 in “Contact dermatitis” Avoiding dyed wigs and clothing improved severe allergic reactions in a woman treated with diphencyprone.
March 2014 in “Journal of The American Academy of Dermatology” Azathioprine may be an effective treatment for severe hair loss.
January 2024 in “JAAD case reports” Netherton syndrome can cause severe and chronic vulvovaginal symptoms that may improve with continuous oral contraceptives.
July 2022 in “International journal of dermatology, venereology and leprosy sciences” More frequent and severe skin problems are linked to higher daily alcohol consumption.
1 citations
,
October 2021 in “Deleted Journal” Dupilumab can help regrow hair and improve skin conditions in patients with severe atopic dermatitis and alopecia areata.
February 2026 in “International Journal of Homoeopathic Sciences” Homeopathy helped regrow hair in a severe hair loss case.
3 citations
,
January 2021 in “Molecular genetics & genomic medicine” The study found two new mutations in a Chinese patient with severe biotinidase deficiency.
June 2026 in “Barind Medical College Journal” Misuse of topical steroids worsens skin infections, causing unusual and severe symptoms.
Nicolaides-Baraitser syndrome may cause eczema and hair loss, needing early skin care and treatment.
COVID-19 can cause various skin issues, from mild rashes to severe conditions.
August 2014 in “Springer eBooks” Certain gene mutations can weaken the skin barrier and, when combined with environmental factors, lead to eczema and severe itching.
8 citations
,
November 2020 in “Journal of the European Academy of Dermatology and Venereology” COVID-19 led to fewer dermatology admissions in Hubei, China, with more severe cases and increased eczema due to mask use and hand disinfectants.
May 2026 in “SKIN The Journal of Cutaneous Medicine” Bimekizumab can improve scarring alopecia in severe psoriasis.
May 2024 in “International journal of medicine and psychology.” Depression worsens eczema severity, increases inflammation, and lowers quality of life.
5 citations
,
January 2009 in “International Journal of Trichology” Two siblings had a rare hair condition with banded hair, which doesn't need treatment.