75 citations
,
March 2023 in “JAMA Dermatology” Alopecia areata and its severe forms are becoming more common, especially among females, adults, and people in the Northeast.
69 citations
,
December 2006 in “Archives of dermatology” Adalimumab may cause severe hair loss in some patients.
51 citations
,
December 2011 in “The Journal of Dermatology” New treatments for severe hair loss often fail, but some patients see hair regrowth with specific therapies, and treatment should be tailored to the individual's situation.
51 citations
,
January 1997 in “PubMed” GABEB is a less severe skin condition caused by a gene mutation affecting collagen, leading to blisters and other symptoms.
50 citations
,
October 1986 in “European journal of pediatrics” A boy with severe Vitamin D-resistant rickets did not respond to treatment and lacked a common symptom, suggesting a need for alternative treatments.
48 citations
,
February 1998 in “British Journal of Dermatology” Thallium poisoning can cause severe neurological symptoms and hair loss.
46 citations
,
January 2005 in “PubMed” Older men with severe symptoms and larger prostates should focus on prevention, using finasteride and alpha-blockers to manage acute urinary retention.
39 citations
,
October 2015 in “Case Reports” Some people experience severe, long-lasting side effects from fluoroquinolone antibiotics, leading to the recommendation of limited use and increased awareness of these risks.
39 citations
,
April 2009 in “Journal of Plastic Reconstructive & Aesthetic Surgery” The surgery for severe congenital ptosis in children is safe and effective, with good long-term results.
37 citations
,
October 2014 in “JAMA dermatology” A woman with severe hair loss was successfully treated with the drug adalimumab.
35 citations
,
April 2014 in “American Journal of Medical Genetics” Boys with less severe EDA mutations in XLHED have milder symptoms and better sweat and hair production.
35 citations
,
January 2010 in “British Journal of Clinical Pharmacology” Saw Palmetto can cause severe liver damage.
32 citations
,
April 2016 in “Journal of Obstetrics and Gynaecology Research” Women with severe types of PCOS are more likely to have metabolic syndrome, and belly fat is a key predictor of this risk.
30 citations
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September 2018 in “International Journal of Cosmetic Science” Bleaching hair causes severe structural and chemical damage, including protein loss and oxidation.
28 citations
,
April 1936 in “Journal of the American Medical Association” Aloe vera healed severe skin damage and restored normal skin in five weeks.
26 citations
,
June 2020 in “The Journal of Allergy and Clinical Immunology In Practice” A patient developed a severe skin reaction and died after taking hydroxychloroquine for COVID-19.
26 citations
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October 2016 in “Case Reports in Dermatology” A man with severe hair loss saw hair and nail improvement after 10 months on tofacitinib without side effects.
26 citations
,
October 1978 in “JAMA” Minoxidil helps treat severe high blood pressure.
25 citations
,
June 2023 in “Biomedicines” Men generally face more severe COVID-19 outcomes than women, partly due to hormonal differences.
25 citations
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July 2013 in “Actas Dermo-Sifiliográficas” Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.
22 citations
,
January 2021 in “Clinical Therapeutics” Men face more severe COVID-19 outcomes, while women are more likely to have long-term symptoms.
22 citations
,
January 2009 in “Advances in experimental medicine and biology” FOXN1 mutations cause severe immunodeficiency, hair loss, nail issues, and thymus defects.
20 citations
,
May 2007 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” Etanercept effectively treated a severe skin condition when other treatments failed.
20 citations
,
September 1983 in “Archives of dermatology” The new synthetic retinoid RO 13-6298 effectively treated severe psoriasis at low doses with manageable side effects.
19 citations
,
June 2018 in “Breast Cancer Research and Treatment” Scalp cooling effectively prevents severe hair loss in breast cancer patients treated with docetaxel and is safe.
18 citations
,
November 2018 in “Annals of the Academy of Medicine Singapore” Sulfasalazine can cause severe allergic reactions leading to long-term autoimmune issues like hair loss and skin discoloration.
18 citations
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November 2009 in “Calcified tissue international” A genetic mutation caused severe rickets and alopecia in an Indian patient, but high-dose calcium and phosphate treatment improved their condition.
17 citations
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April 1975 in “The Journal of Pediatrics” Minoxidil effectively controls severe high blood pressure in children with few side effects.
16 citations
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March 2018 in “Plastic and Reconstructive Surgery – Global Open” Early surgical treatment for severe facial injuries from high-energy impacts leads to better recovery.
16 citations
,
May 2011 in “Dermatologic therapy” Effective treatments for severe alopecia areata are still lacking.