121 citations
,
November 2020 in “Endocrine” Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.
91 citations
,
December 2017 in “Systems Biology in Reproductive Medicine” Lower SHBG levels may increase the risk of PCOS.
47 citations
,
May 2020 in “Cardiovascular Research” The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.
45 citations
,
March 2015 in “Clinical Endocrinology” Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.
42 citations
,
June 2020 in “Seminars in Oncology” Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.
32 citations
,
February 2019 in “Journal of neurochemistry” Sex hormones affect brain injury differently in males and females.
31 citations
,
August 2020 in “EClinicalMedicine” Male cancer patients have a higher risk of severe illness and death from COVID-19 than female patients.
24 citations
,
November 2015 in “Annals of Nutrition and Metabolism” Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.
7 citations
,
October 2017 in “The Prostate” Baldness in men with prostate cancer is linked to higher levels of certain sex hormones, but chest hair density is not.
2 citations
,
November 2012 in “InTech eBooks” The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.
1 citations
,
October 2023 in “Frontiers in endocrinology” Regulating certain sex hormones may help delay facial aging.
February 2026 in “Diabetes Metabolic Syndrome and Obesity” Higher basal metabolic rate increases the risk of non-alcoholic fatty liver disease, especially in Chinese people, and may require tailored management.
December 2023 in “Kiểm nghiệm và An toàn thực phẩm/Kiểm nghiệm và An toàn thực phẩm (online)” The method detected sex hormones in some health supplements, with one containing banned testosterone.
Sex hormones likely did not affect COVID-19 outcomes in South Korea.
21 citations
,
November 2014 in “Journal of Endocrinological Investigation” Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.
1 citations
,
December 2025 in “Selçuk tıp dergisi/Selçuk Üniversitesi Tıp Fakültesi dergisi” Lower 2D:4D finger ratios in HS patients suggest prenatal hormone influence on the disease.
Oral lichen planus is not linked to sex hormone levels.
March 2017 in “Journal of Dermatology” Different hair loss patterns may be linked to varying male hormone levels.
9 citations
,
January 1997 in “Endocrine Journal” Gonadal biopsy is the best method to diagnose gonadal dysgenesis.
5 citations
,
August 2018 in “Ocular immunology and inflammation” Methotrexate side effects vary by race and sex.
33 citations
,
January 2017 in “Conservation physiology” Measuring reproductive hormones in brown bear hair could help identify their sex and reproductive state, but better collection methods or lab techniques are needed.
28 citations
,
May 2015 in “Addiction Biology” Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.
26 citations
,
September 2015 in “Journal of The American Academy of Dermatology” Spironolactone may effectively treat female hair loss, especially with hyperandrogenism signs.
21 citations
,
May 2016 in “Progress in Neuro-Psychopharmacology and Biological Psychiatry” Diazepam's effects on anxiety and memory differ between male and female rats due to hormonal influences.
20 citations
,
September 1978 in “International Journal of Dermatology” Hair growth is influenced by factors like genetics and nutrition, and more research is needed to understand hair loss and growth mechanisms.
1 citations
,
January 2016 in “Journal of Microbial & Biochemical Technology” The Free Androgen Index (FAI) is the best indicator of early hair loss in men before age 30.
Testosterone pellet therapy may better address hormone imbalances in aging by focusing on local hormone production and symptom relief.
2295 citations
,
August 2012 in “The international journal of transgenderism/International journal of transgenderism” The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.
403 citations
,
November 2005 in “Journal of Endocrinology” Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.
166 citations
,
October 2018 in “Endocrine Reviews” Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.