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Australian doctors experienced in adult transgender healthcare mostly prescribe intramuscular testosterone and oral estradiol, recommend mental health assessments before hormone therapy, and support improved training and guidelines.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Hormone therapy can improve mental health and quality of life for people with gender dysphoria, but long-term effects need more research.

Cyclosporine A therapy changes sex hormone levels differently in pre-menopausal and post-menopausal women with primary biliary cirrhosis.

Hormonal contraceptives and therapies regulate organ functions and treat various conditions.

Metformin works better for adolescent girls with PCOS who have certain genetic variations.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

SHBG may be a useful early indicator and treatment target for PCOS.

Prostate cancer patients need early psychological and sexual support during radiotherapy to improve their quality of life.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Sex hormone therapy is effective for certain skin conditions like acne and seborrhea, but less so for female hair loss and excessive hair growth.

Spironolactone may help reduce excessive hair growth in women with high male hormone levels.

Cross-sex hormone treatment in transsexual individuals helps understand how sex hormones affect diseases like heart disease and diabetes.

The document concludes that there is a significant lack of reporting on the sex and age of cells in skin research, which could affect clinical trials and treatments.

Spironolactone may effectively treat female hair loss, especially with hyperandrogenism signs.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

Combination therapy with oral contraceptives and spironolactone improves hair growth, menstrual issues, and acne in women with PCOS.

Hormone therapy affects cancer risks in transgender individuals differently than in cisgender people, and more research is needed to understand these risks and improve cancer screening guidelines.

Testosterone therapy for postmenopausal women appears safe and may protect against heart disease, but requires constant monitoring and more research for long-term effects.

Hormonal contraceptives and related compounds can increase health risks like thrombosis and affect sexual function.

Testosterone pellet therapy may better address hormone imbalances in aging by focusing on local hormone production and symptom relief.

Sex hormones affect hair growth and loss, and treatments for related hair diseases include various medications, hair transplantation, and light therapy.

Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.

Low testosterone and SHBG levels are linked to higher COVID-19 death rates.

Local hormonal treatment for vulvovaginal atrophy is likely safe for women with estrogen receptor-positive breast cancer on aromatase inhibitors.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

The combination therapy effectively treats infertility in PCOS without major side effects.

Feminizing hormone therapy increases kidney filtration rate.