research The Biology of Hair Follicles
Hair follicle biology advancements may lead to better hair growth disorder treatments.
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research Vitiligo: A comprehensive overview
Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.
research Pharmacology of anabolic steroids
Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.
research Improving human forensics through advances in genetics, genomics and molecular biology
DNA profiling in forensics has improved, but predicting physical traits and ancestry from DNA has limitations and requires ethical consideration.
research Overweight and Obesity in Children and Adolescents
Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.
research American Association of Clinical Endocrinologists, American College of Endocrinology, and Androgen Excess and PCOS Society Disease State Clinical Review: Guide to the Best Practices in the Evaluation and Treatment of Polycystic Ovary Syndrome - Part 1
The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.
research Evidence-Based and Potential Benefits of Metformin in the Polycystic Ovary Syndrome: A Comprehensive Review
Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
research Wnt Signaling in Skin Development, Homeostasis, and Disease
Wnt signaling is crucial for skin development and health, and its disruption can cause skin diseases.
research Androgen Therapy in Women: A Reappraisal: An Endocrine Society Clinical Practice Guideline
The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.
research The Current Landscape for Direct-to-Consumer Genetic Testing: Legal, Ethical, and Policy Issues
The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.
research Screening for 21-hydroxylase–deficient nonclassic adrenal hyperplasia among hyperandrogenic women: a prospective study
Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.
research Androgens and hair growth
Androgens can both increase and decrease hair growth in different parts of the body.
research The diagnosis and treatment of iron deficiency and its potential relationship to hair loss
Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.
research Androgens and human hair growth
Androgens can cause hair growth in some areas and hair loss on the scalp.
research Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing
The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.
research Estrogens and the skin
Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.
research The pathophysiology of polycystic ovary syndrome: trying to understand PCOS and its endocrinology
The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.
research Experimental Induction of Alopecia Areata-Like Hair Loss in C3H/HeJ Mice Using Full-Thickness Skin Grafts
Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.
research Obesity and the skin
Obesity is linked to various skin problems and may increase the risk of skin cancer.
research Function and underlying mechanisms of seasonal colour moulting in mammals and birds: what keeps them changing in a warming world?
Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.
research A Guide to Assessing Damage Response Pathways of the Hair Follicle: Lessons From Cyclophosphamide-Induced Alopecia in Mice
The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.
research First use of thymus transplantation therapy for FOXN1 deficiency (nude/SCID): a report of 2 cases
Thymus transplantation successfully restored immune function in infants with FOXN1 deficiency.
research Diagnosis and management of the dermatologic manifestations of the polycystic ovary syndrome
The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.
research Elemental hair analysis: A review of procedures and applications
Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.
research EMQN best practice guidelines for molecular genetic testing and reporting of 21-hydroxylase deficiency
The guidelines ensure accurate genetic testing and reporting for 21-hydroxylase deficiency.
research Female pattern hair loss
FPHL is a common, age-related, genetic hair loss with unclear causes and limited treatment options.
research Epidermal stem cells and skin tissue engineering in hair follicle regeneration
Hair follicle regeneration needs special conditions and young cells.
research Are the cutaneous manifestations during or due to SARS-CoV-2 infection/COVID-19 frequent or not? Revision of possible pathophysiologic mechanisms
Skin problems in COVID-19 patients are rare and may be due to the body's complex immune response or blood clotting issues.
research Androgen excess: Investigations and management
The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.
research Adverse effects of common medications on male fertility
Some common medications can harm male fertility, but many effects can be reversed.