research Significant Effects of Mild Endogenous Hormonal Changes in Humans: Considerations for Low-Dose Testing
Small hormonal imbalances can cause significant health problems, so more sensitive testing for hormone-disrupting chemicals is needed.
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research The effect of gonadoliberin analog treatment in precocious puberty on polycystic ovarian syndrome prevalence in adulthood
Treating early puberty with hormone therapy may increase the risk of polycystic ovary syndrome in adults.
research To study hypoactive sexual desire disorder in a fragile X carrier female successfully treated with local testosterone application
Local testosterone treatment improved sexual desire in a female with fragile X syndrome.
research Disorders of sex development (DSD) 46.XY due to type 2 5-α reductase deficiency in three siblings: Case report from a low-resource setting
Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.
research Deletion of Deoxyribonucleic Acid Binding Domain of the Vitamin D Receptor Abrogates Genomic and Nongenomic Functions of Vitamin D
Removing part of the vitamin D receptor stops vitamin D from working properly.
research Current evaluation of amenorrhea
The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.
research Current evaluation of amenorrhea
Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.
research Skin manifestations of chronic kidney disease
Chronic kidney disease can cause skin problems that affect patient quality of life, and treating these conditions can improve outcomes.
research Focal and Generalized Alopecia
The document concludes that hair loss in cats is caused by various factors, including allergies, mites, infections, and hormonal issues, with treatments varying accordingly.
research Determination of serum 25-hydroxyvitamin D levels in patients with alopecia areata and their comparison with levels in healthy controls: A cross-sectional study
Patients with alopecia areata may have lower vitamin D levels than healthy people.
research Female Antiandrogens
Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.
research Climacteric Commentaries
Long-term estrogen therapy in postmenopausal women can improve certain health markers, hair loss is common regardless of hormone use, stopping estrogen doesn't increase breast cancer risk, smoking does, and a balanced BMI is linked to lower mortality.
research Symmetrical alopecia in the dog
The conclusion is that a systematic approach is key for treating symmetrical alopecia in dogs, but treatment may not always be necessary.
research The Association Between Low Grade Systemic Inflammation and Skin Diseases: A Cross-sectional Survey in the Northern Finland Birth Cohort 1966
Adults with certain skin conditions may have higher levels of inflammation in their body.
research Immune mechanisms associated with sex-based differences in severe COVID-19 clinical outcomes
Females have stronger immune responses to COVID-19 than males, leading to better outcomes.
research Prolactin: A Mammalian Stress Hormone and Its Role in Cutaneous Pathophysiology
Prolactin affects skin health and may lead to new treatments for skin and hair issues.
research Dermatologic care of patients with differences of sex development
Dermatologists are crucial in providing personalized care for patients with sex development differences.
research Contemporary medical therapy for polycystic ovary syndrome
New treatments for PCOS focus on insulin resistance and reducing testosterone levels, along with traditional hormone therapies.
research Curtailing PCOS
Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.
research Do follicles matter? Testing the effect of follicles on hair cortisol levels
Hair follicles increase hair cortisol levels, so consistent hair collection methods are important.
research Alopecia in three macaque species housed in a laboratory environment
Different monkey species in a lab showed varying levels of hair loss due to factors like type, sex, age, season, and living conditions.
research ODP398 A Novel NR5A1 Gene Mutation Causing 46, XY DSD Without Adrenal Insufficiency in an Immigrant Boy from Dominican Republic
A boy with a new NR5A1 gene mutation has a sex development disorder without affecting his adrenal glands.
research Idiopathic Hirsutism*
The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.
research Treatment of hirsutism by finasteride and flutamide in women with polycystic ovary syndrome
Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.
research Polycystic Ovary Syndrome in Adolescents
The document concludes that diagnosing PCOS in teenagers is difficult and should focus on specific hormone levels and menstrual irregularities, while also considering treatment for symptoms and related health issues.
research Ovarian Hemangioma With Stromal Luteinization
The removed ovarian tumor was a rare type of blood vessel tumor that improved the patient's symptoms and hormone levels after surgery.
research Ratio of ovarian stroma and total ovarian area by ultrasound in prediction of hyperandrogenemia in reproductive-aged Thai women with polycystic ovary syndrome: A diagnostic test
Ultrasound measurement of the ovarian stroma to total area ratio is not a reliable single predictor of high male hormone levels in Thai women with PCOS, but works better when combined with clinical signs.
research The association of androgenetic alopecia and insulin resistance is independent of hyperandrogenemia: A case-control study
Hair loss is linked to insulin resistance in women, regardless of hormone levels.
research Study of Frontal Hairline Patterns in Spanish Caucasian Women
Most Spanish Caucasian women have a widow's peak, and their hormone levels suggest they process certain hormones faster.
research Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways
Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.