research New lifestyle drugs and somatoform disorders in dermatology
The article concludes that dermatologists should prescribe lifestyle drugs carefully and consider mental health treatments for patients with disorders like BDD.
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research The effect of spironolactone on genital skin 5α-reductase activity
Spironolactone reduces the enzyme activity that converts testosterone to DHT, helping treat excessive hair growth in women.
research European Consensus on the evaluation of women presenting with excessive hair growth
Experts made a guide to help doctors evaluate women with too much hair growth.
research Androgenic disorders
The book is a valuable reference on androgenic disorders for professionals but not suitable for laypeople or medical students.
research Advances in Knowledge of Androgens: How Intentional and Accidental Neurosteroid Changes Inform Us of Their Action and Role
Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.
research Proscar@ (Finasteride) inhibits 5α-reductase activity in the ovaries and testes of Lytechinus variegatus Lamarck (Echinodermata: Echinoidea)
Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.
research A role for steroid 5 alpha-reductase 1 in vascular remodeling during endometrial decidualization
The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.
research Genetic and other epidemiological risk factors of infants and children with hypospadias: a case control study
Older parental age, rural living, and specific genetic mutations increase hypospadias risk in children.
research 133 Grey-Scale Penile Ultrasound Findings in Young Men with Erectile Dysfunction (ED) Who Used Finasteride for Androgenic Alopecia: A Retrospective Review
Finasteride for hair loss can cause erectile dysfunction due to tissue fibrosis.
research Review of: "“Toupee or not Toupee?” Sic (et Non). Social perceptions of Male Pattern Baldness (Androgenetic Alopecia)"
The review suggests the study on male pattern baldness needs more detail on sample size, methodology, bias, and ethical considerations.
research Critical Developmental Periods for Effects on Male Rat Genitalia Induced by Finasteride, a 5α-Reductase Inhibitor
Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.
research Finasteride treatment and neuroactive steroid formation.
Finasteride treatment can decrease certain steroids and increase others, possibly leading to depression symptoms in some cases.
research Clinical Management of Youth with Gender Dysphoria in Vancouver
Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.
research A Mutation of the Androgen Receptor Associated with Partial Androgen Resistance, Familial Gynecomastia, and Fertility*
A subtle androgen receptor abnormality can allow normal male development and sometimes fertility despite partial androgen resistance.
research Effects of finasteride, a 5 alpha-reductase inhibitor, on circulating androgens and gonadotropin secretion in hirsute women
research The Implication of Neuroactive Steroids in Tourette's Syndrome Pathogenesis: A Role for 5α‐Reductase?
Neuroactive steroids and the enzyme 5α-reductase might be involved in the development of Tourette's syndrome.
research Interactions between Lower Urinary Tract Symptoms and Cardiovascular Risk Factors Determine Distinct Patterns of Erectile Dysfunction: A Latent Class Analysis
Men's age, urinary symptoms, and heart health risks create different types of erectile dysfunction.
research NEW TREATMENTS OF HYPERANDROGENISM AND HIRSUTISM
Hirsutism causes significant psychological distress in women.
research The Collision Regions Between Two Epidemic Models: SIR vs. SEIR
Pediatric androgenetic alopecia is underrecognized, and clinical evaluation is crucial for diagnosis, with potential treatments including minoxidil and finasteride.
research Effects of sex steroid hormones and their metabolites on neuronal injury caused by oxygen-glucose deprivation/reoxygenation in organotypic hippocampal slice cultures
Progesterone and testosterone protect brain cells from damage through specific pathways.
research Editor's Mailbox
Robert T. Leonard Jr. disagrees with Max Rubin's negative views on hair loss treatment, advocating for hormonal tests in women and supporting the use of medications and surgery for androgenetic alopecia.
research Androgenetic Alopecia: Stress of Discovery
Hair loss discovery causes stress; talking to dermatologists helps.
research Hyperandrogenism and woman's sexual function
Hyperandrogenism does not affect young women's sexual function.
research 837 Characterization of cutaneous hormone production through analysis of skin secretions
Skin produces different hormones depending on body part and sex, and a new method can measure them.
research The Polycystic Ovary Syndrome Evolutionary Paradox: a Genome-Wide Association Studies–Based, in silico, Evolutionary Explanation
The research suggests that the global distribution of PCOS is likely due to historical human migration and that genes affecting PCOS may have different impacts on males and females.
research Male Androgenetic Alopecia
New understanding of hair loss could lead to better treatments.
research Study on the zona pellucida 4 (ZP4) gene sequence and its expression in the ovaries of patients with polycystic ovary syndrome
The research suggests that the ZP4 gene is linked to egg development in women with PCOS but requires more study to understand its role in infertility.
research A comparison of the manifestation of psychopathic traits between women with and without Polycystic Ovary Syndrome (PCOS)
Women with and without PCOS show no significant differences in psychopathic traits.
research Association between serum zinc levels and androgenetic alopecia: a systematic review and meta‐analysis
research Post‐Finasteride Syndrome or Pre‐Existing Vulnerability? Rethinking Patient Selection
Post-finasteride syndrome may be linked to pre-existing psychological issues, not just the drug.