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An N-Ethyl-N-Nitrosourea Induced Corticotropin-Releasing Hormone Promoter Mutation Provides a Mouse Model for Endogenous Glucocorticoid Excess

research An N-Ethyl-N-Nitrosourea Induced Corticotropin-Releasing Hormone Promoter Mutation Provides a Mouse Model for Endogenous Glucocorticoid Excess

27 citations , December 2013 in “Endocrinology”

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

research Novel Missense Mutation in the P-Box of Androgen Receptor in a Patient with Androgen Insensitivity Syndrome

3 citations , January 2008 in “Endocrine journal”

A new mutation linked to partial Androgen Insensitivity Syndrome and prostate cancer was found in a patient unhappy with their female gender assignment.

research 699 Pharmacological blockade of the CX3CR1/CX3CL1 fractalkine axis prevents alopecia areata in C3H/HeJ mice

April 2021 in “Journal of Investigative Dermatology”

research Nagashima-Type Palmoplantar Keratosis: A Common Asian Type Caused by SERPINB7 Protease Inhibitor Deficiency

24 citations , July 2014 in “Journal of Investigative Dermatology”

Nagashima-type palmoplantar keratosis in Asians is caused by a SERPINB7 gene mutation.

research The role of Atg5 gene in tumorigenesis under autophagy deficiency conditions

4 citations , June 2024 in “The Kaohsiung Journal of Medical Sciences”

Atg5 can promote tumors when autophagy is deficient but suppresses them under normal conditions.

research Activated Polyamine Catabolism Depletes Acetyl-CoA Pools and Suppresses Prostate Tumor Growth in TRAMP Mice

91 citations , July 2004 in “Journal of Biological Chemistry”

Overexpressing SSAT enzyme reduces prostate tumor growth in mice.

research A BIOCHEMICAL MARKER IN A DOMINANT MOUSE TRAIT

April 1974 in “Pediatric Research”

The Naked (N) trait in mice is linked to lower glycine and tyrosine in hair proteins.

research c-MYC-Induced Sebaceous Gland Differentiation Is Controlled by an Androgen Receptor/p53 Axis

60 citations , February 2013 in “Cell reports”

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

research Granulocyte colony stimulating factor promotes scarless tissue regeneration

4 citations , September 2024 in “Cell Reports”

Granulocyte colony stimulating factor helps heal wounds without scars.

research Preclinical Pharmacology, Antitumor Activity, and Development of Pharmacodynamic Markers for the Novel, Potent AKT Inhibitor CCT128930

65 citations , February 2011 in “Molecular cancer therapeutics”

CCT128930 is a promising new drug that effectively targets and inhibits a cancer-related protein, showing potential for cancer treatment.

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